EC Number |
Inhibitors |
Structure |
---|
3.5.1.28 | 1,10-phenanthroline |
0.005 mM, complete inhibition after 30 min, activity can be restored by 0.1 mM ZnSO4 |
|
3.5.1.28 | 1,10-phenanthroline |
strong, 5 mM, 94% inhibition |
|
3.5.1.28 | 1,10-phenanthroline |
inactivation through depletion of zinc ions |
|
3.5.1.28 | 1,10-phenanthroline |
- |
|
3.5.1.28 | 1,10-phenanthroline |
complete inhibition; enzyme results in complete loss of activity, when dialyzed overnight against the metal chelator |
|
3.5.1.28 | benzoyl-Arg-p-nitroanilide |
inhibition: moderately at 1 mM, completely at 10 mM |
|
3.5.1.28 | beta-mercaptoethanol |
- |
|
3.5.1.28 | CdCl2 |
- |
|
3.5.1.28 | CDTA |
about 90% inhibition; enzyme results in about 90% loss of activity, when dialyzed overnight against the metal chelator. Some restoration of activity is observed with all of the metal salts (10 mM ZnCl2, MgCl2, CaCl2, CoCl2, or NiCl). The addition of ZnCl2, MgCl2, and CaCl2 is the most effective, restoring 70-80% of the activity, with NiCl2 restoring about 50% and CoCl2 the least effective at only about 25% |
|
3.5.1.28 | choline |
- |
|