EC Number |
Inhibitors |
Structure |
---|
2.4.3.2 | Ba2+ |
10 mM BaCl2, 12% inhibition |
|
2.4.3.2 | beta-D-Gal-(1->3)-beta-D-GalNAc |
the enzyme exhibits competitive inhibition between all kinds of acceptors; the enzyme exhibits noncompetitive inhibition between ganglioside GA1 and beta-D-Gal-(1->3)-beta-D-GalNAc or between ganglioside GA1 and [asialofeuin]-(O-3-(alpha-Neu5Ac-(2->3)-beta-D-Gal-(1->3)-alpha-D-GalNAc-(1->)))-L-serine |
|
2.4.3.2 | Ca2+ |
10 mM CaCl2, 39% inhibition |
|
2.4.3.2 | Cd2+ |
10 mM CdCl2, 85% inhibition |
|
2.4.3.2 | CMP-N-acetyl-beta-neuraminate |
inhibition is observed at a concentration greater than 0.25 mM |
|
2.4.3.2 | CMP-N-acetylneuraminate |
above 0.2 M |
|
2.4.3.2 | Co2+ |
10 mM CoCl2, 44% inhibition |
|
2.4.3.2 | Cu2+ |
10 mM CuCl2, complete inhibition |
|
2.4.3.2 | ganglioside GA1 |
the enzyme exhibits competitive inhibition between all kinds of acceptors; the enzyme exhibits noncompetitive inhibition between ganglioside GA1 and beta-D-Gal-(1->3)-beta-D-GalNAc or between ganglioside GA1 and [asialofeuin]-(O-3-(alpha-Neu5Ac-(2->3)-beta-D-Gal-(1->3)-alpha-D-GalNAc-(1->)))-L-serine |
|
2.4.3.2 | ganglioside GM3 |
in the presence of Triton CF-54 |
|