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Ligand Ca2+
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Basic Ligand Information
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open all tablesRoles as Enzyme Ligand
In Vivo Substrate in Enzyme-catalyzed Reactions (50 results)
top
EC NUMBER 
PROVEN IN VIVO REACTION
REACTION DIAGRAM
LITERATURE
ENZYME 3D STRUCTURE
[apoaequorin] + coelenterazine + O2 + 3 Ca2+ = [excited state blue fluorescent protein] + CO2
-
ATP + H2O + Ca2+/cis = ADP + phosphate + Ca2+/trans
ATP + H2O + Ca2+/cis = ADP + phosphate + Ca2+/trans
ATP + H2O + Ca2+/cis = ADP + phosphate + Ca2+/trans
ATP + H2O + Ca2+/cis = ADP + phosphate + Ca2+/trans
ATP + H2O + Ca2+/cis = ADP + phosphate + Ca2+/trans
ATP + H2O + Ca2+/cis = ADP + phosphate + Ca2+/trans
ATP + H2O + Ca2+/cis = ADP + phosphate + Ca2+/trans
ATP + H2O + Ca2+[side 1] + H+[side 2] = ADP + phosphate + Ca2+[side 2] + H+[side 1]
ATP + H2O + Ca2+[side 1] + H+[side 2] = ADP + phosphate + Ca2+[side 2] + H+[side 1]
ATP + H2O + Ca2+[side 1] + H+[side 2] = ADP + phosphate + Ca2+[side 2] + H+[side 1]
ATP + H2O + Ca2+[side 1] + H+[side 2] = ADP + phosphate + Ca2+[side 2] + H+[side 1]
ATP + H2O + Ca2+[side 1] + H+[side 2] = ADP + phosphate + Ca2+[side 2] + H+[side 1]
ATP + H2O + Ca2+[side 1] + H+[side 2] = ADP + phosphate + Ca2+[side 2] + H+[side 1]
ATP + H2O + Ca2+[side 1] + H+[side 2] = ADP + phosphate + Ca2+[side 2] + H+[side 1]
ATP + H2O + Ca2+[side 1] = ADP + phosphate + Ca2+[side 2]
733067, 733416, 734304, 751396, 733277, 733466, 734224, 734517, 735113, 748570, 749980, 750486, 750998, 751700, 752192, 733404, 733790, 750281, 734423, 733829, 750181, 750217, 734940, 751369, 733998, 733830, 749857, 752240, 751803, 734372, 750573, 734209, 734516, 750543, 751099, 762019, 761957, 751094, 734295, 733454, 751523, 751525, 750694, 761208, 735233
ATP + H2O + Ca2+[side 1] = ADP + phosphate + Ca2+[side 2]
733067, 733416, 734304, 751396, 733277, 733466, 734224, 734517, 735113, 748570, 749980, 750486, 750998, 751700, 752192, 733404, 733790, 750281, 734423, 733829, 750181, 750217, 734940, 751369, 733998, 733830, 749857, 752240, 751803, 734372, 750573, 734209, 734516, 750543, 751099, 762019, 761957, 751094, 734295, 733454, 751523, 751525, 750694, 761208, 735233
ATP + H2O + Ca2+[side 1] = ADP + phosphate + Ca2+[side 2]
733067, 733416, 734304, 751396, 733277, 733466, 734224, 734517, 735113, 748570, 749980, 750486, 750998, 751700, 752192, 733404, 733790, 750281, 734423, 733829, 750181, 750217, 734940, 751369, 733998, 733830, 749857, 752240, 751803, 734372, 750573, 734209, 734516, 750543, 751099, 762019, 761957, 751094, 734295, 733454, 751523, 751525, 750694, 761208, 735233
ATP + H2O + Ca2+[side 1] = ADP + phosphate + Ca2+[side 2]
733067, 733416, 734304, 751396, 733277, 733466, 734224, 734517, 735113, 748570, 749980, 750486, 750998, 751700, 752192, 733404, 733790, 750281, 734423, 733829, 750181, 750217, 734940, 751369, 733998, 733830, 749857, 752240, 751803, 734372, 750573, 734209, 734516, 750543, 751099, 762019, 761957, 751094, 734295, 733454, 751523, 751525, 750694, 761208, 735233
ATP + H2O + Ca2+[side 1] = ADP + phosphate + Ca2+[side 2]
733067, 733416, 734304, 751396, 733277, 733466, 734224, 734517, 735113, 748570, 749980, 750486, 750998, 751700, 752192, 733404, 733790, 750281, 734423, 733829, 750181, 750217, 734940, 751369, 733998, 733830, 749857, 752240, 751803, 734372, 750573, 734209, 734516, 750543, 751099, 762019, 761957, 751094, 734295, 733454, 751523, 751525, 750694, 761208, 735233
ATP + H2O + Ca2+[side 1] = ADP + phosphate + Ca2+[side 2]
733067, 733416, 734304, 751396, 733277, 733466, 734224, 734517, 735113, 748570, 749980, 750486, 750998, 751700, 752192, 733404, 733790, 750281, 734423, 733829, 750181, 750217, 734940, 751369, 733998, 733830, 749857, 752240, 751803, 734372, 750573, 734209, 734516, 750543, 751099, 762019, 761957, 751094, 734295, 733454, 751523, 751525, 750694, 761208, 735233
ATP + H2O + Ca2+[side 1] = ADP + phosphate + Ca2+[side 2]
733067, 733416, 734304, 751396, 733277, 733466, 734224, 734517, 735113, 748570, 749980, 750486, 750998, 751700, 752192, 733404, 733790, 750281, 734423, 733829, 750181, 750217, 734940, 751369, 733998, 733830, 749857, 752240, 751803, 734372, 750573, 734209, 734516, 750543, 751099, 762019, 761957, 751094, 734295, 733454, 751523, 751525, 750694, 761208, 735233
In Vivo Product in Enzyme-catalyzed Reactions (42 results)
EC NUMBER
PROVEN IN VIVO REACTION
REACTION DIAGRAM
LITERATURE
ENZYME 3D STRUCTURE
ATP + H2O + Ca2+[side 1] + H+[side 2] = ADP + phosphate + Ca2+[side 2] + H+[side 1]
ATP + H2O + Ca2+[side 1] + H+[side 2] = ADP + phosphate + Ca2+[side 2] + H+[side 1]
ATP + H2O + Ca2+[side 1] + H+[side 2] = ADP + phosphate + Ca2+[side 2] + H+[side 1]
ATP + H2O + Ca2+[side 1] + H+[side 2] = ADP + phosphate + Ca2+[side 2] + H+[side 1]
ATP + H2O + Ca2+[side 1] + H+[side 2] = ADP + phosphate + Ca2+[side 2] + H+[side 1]
ATP + H2O + Ca2+[side 1] + H+[side 2] = ADP + phosphate + Ca2+[side 2] + H+[side 1]
ATP + H2O + Ca2+[side 1] + H+[side 2] = ADP + phosphate + Ca2+[side 2] + H+[side 1]
Substrate in Enzyme-catalyzed Reactions (126 results)
EC NUMBER
REACTION
REACTION DIAGRAM
LITERATURE
ENZYME 3D STRUCTURE
[apoaequorin] + coelenterazine + O2 + 3 Ca2+ = [excited state blue fluorescent protein] + CO2
-
[apoaequorin] + cp-coelenterazine + O2 + 3 Ca2+ = [excited state blue fluorescent protein] + CO2
-
[apoaequorin] + f-coelenterazine + O2 + 3 Ca2+ = [excited state blue fluorescent protein] + CO2
-
[apoaequorin] + h-coelenterazine + O2 + 3 Ca2+ = [excited state blue fluorescent protein] + CO2
-
[apoaequorin] + hcp-coelenterazine + O2 + 3 Ca2+ = [excited state blue fluorescent protein] + CO2
-
ATP + H2O + Ca2+/cis = ADP + phosphate + Ca2+/trans
670677, 695986, 701312, 656099, 667623, 695512, 696391, 697160, 697167, 697168, 697858, 698973, 700358, 701104, 697151, 699293, 720447, 656229, 695859, 695863, 697684, 698270, 698857, 698885, 670757, 700969, 699788, 669657, 669673, 696294, 696744, 697629, 700293, 700805, 695867, 669402, 667650, 669312, 669498, 667825, 667995, 668626, 669343, 669345, 670493, 667604, 670669, 668606, 695858, 712588, 712744
ATP + H2O + Ca2+/cis = ADP + phosphate + Ca2+/trans
670677, 695986, 701312, 656099, 667623, 695512, 696391, 697160, 697167, 697168, 697858, 698973, 700358, 701104, 697151, 699293, 720447, 656229, 695859, 695863, 697684, 698270, 698857, 698885, 670757, 700969, 699788, 669657, 669673, 696294, 696744, 697629, 700293, 700805, 695867, 669402, 667650, 669312, 669498, 667825, 667995, 668626, 669343, 669345, 670493, 667604, 670669, 668606, 695858, 712588, 712744
ATP + H2O + Ca2+/cis = ADP + phosphate + Ca2+/trans
670677, 695986, 701312, 656099, 667623, 695512, 696391, 697160, 697167, 697168, 697858, 698973, 700358, 701104, 697151, 699293, 720447, 656229, 695859, 695863, 697684, 698270, 698857, 698885, 670757, 700969, 699788, 669657, 669673, 696294, 696744, 697629, 700293, 700805, 695867, 669402, 667650, 669312, 669498, 667825, 667995, 668626, 669343, 669345, 670493, 667604, 670669, 668606, 695858, 712588, 712744
ATP + H2O + Ca2+/cis = ADP + phosphate + Ca2+/trans
670677, 695986, 701312, 656099, 667623, 695512, 696391, 697160, 697167, 697168, 697858, 698973, 700358, 701104, 697151, 699293, 720447, 656229, 695859, 695863, 697684, 698270, 698857, 698885, 670757, 700969, 699788, 669657, 669673, 696294, 696744, 697629, 700293, 700805, 695867, 669402, 667650, 669312, 669498, 667825, 667995, 668626, 669343, 669345, 670493, 667604, 670669, 668606, 695858, 712588, 712744
ATP + H2O + Ca2+/cis = ADP + phosphate + Ca2+/trans
670677, 695986, 701312, 656099, 667623, 695512, 696391, 697160, 697167, 697168, 697858, 698973, 700358, 701104, 697151, 699293, 720447, 656229, 695859, 695863, 697684, 698270, 698857, 698885, 670757, 700969, 699788, 669657, 669673, 696294, 696744, 697629, 700293, 700805, 695867, 669402, 667650, 669312, 669498, 667825, 667995, 668626, 669343, 669345, 670493, 667604, 670669, 668606, 695858, 712588, 712744
ATP + H2O + Ca2+/cis = ADP + phosphate + Ca2+/trans
670677, 695986, 701312, 656099, 667623, 695512, 696391, 697160, 697167, 697168, 697858, 698973, 700358, 701104, 697151, 699293, 720447, 656229, 695859, 695863, 697684, 698270, 698857, 698885, 670757, 700969, 699788, 669657, 669673, 696294, 696744, 697629, 700293, 700805, 695867, 669402, 667650, 669312, 669498, 667825, 667995, 668626, 669343, 669345, 670493, 667604, 670669, 668606, 695858, 712588, 712744
ATP + H2O + Ca2+/cis = ADP + phosphate + Ca2+/trans
670677, 695986, 701312, 656099, 667623, 695512, 696391, 697160, 697167, 697168, 697858, 698973, 700358, 701104, 697151, 699293, 720447, 656229, 695859, 695863, 697684, 698270, 698857, 698885, 670757, 700969, 699788, 669657, 669673, 696294, 696744, 697629, 700293, 700805, 695867, 669402, 667650, 669312, 669498, 667825, 667995, 668626, 669343, 669345, 670493, 667604, 670669, 668606, 695858, 712588, 712744
ATP + H2O + Ca2+/out = ADP + phosphate + Ca2+/in
210494, 210473, 210481, 210483, 210489, 210491, 719962, 210476, 210480, 210486, 720447, 210495, 210474, 210475, 210478, 210490, 210492, 210493, 210496, 210498, 720644, 210485, 210479, 210482, 210477, 210497, 210487, 210488, 720121, 684657, 719980, 720908, 720903, 720281, 719497, 720136, 719888, 719869, 210484
ATP + H2O + Ca2+/out = ADP + phosphate + Ca2+/in
210494, 210473, 210481, 210483, 210489, 210491, 719962, 210476, 210480, 210486, 720447, 210495, 210474, 210475, 210478, 210490, 210492, 210493, 210496, 210498, 720644, 210485, 210479, 210482, 210477, 210497, 210487, 210488, 720121, 684657, 719980, 720908, 720903, 720281, 719497, 720136, 719888, 719869, 210484
ATP + H2O + Ca2+/out = ADP + phosphate + Ca2+/in
210494, 210473, 210481, 210483, 210489, 210491, 719962, 210476, 210480, 210486, 720447, 210495, 210474, 210475, 210478, 210490, 210492, 210493, 210496, 210498, 720644, 210485, 210479, 210482, 210477, 210497, 210487, 210488, 720121, 684657, 719980, 720908, 720903, 720281, 719497, 720136, 719888, 719869, 210484
ATP + H2O + Ca2+/out = ADP + phosphate + Ca2+/in
210494, 210473, 210481, 210483, 210489, 210491, 719962, 210476, 210480, 210486, 720447, 210495, 210474, 210475, 210478, 210490, 210492, 210493, 210496, 210498, 720644, 210485, 210479, 210482, 210477, 210497, 210487, 210488, 720121, 684657, 719980, 720908, 720903, 720281, 719497, 720136, 719888, 719869, 210484
ATP + H2O + Ca2+/out = ADP + phosphate + Ca2+/in
210494, 210473, 210481, 210483, 210489, 210491, 719962, 210476, 210480, 210486, 720447, 210495, 210474, 210475, 210478, 210490, 210492, 210493, 210496, 210498, 720644, 210485, 210479, 210482, 210477, 210497, 210487, 210488, 720121, 684657, 719980, 720908, 720903, 720281, 719497, 720136, 719888, 719869, 210484
ATP + H2O + Ca2+/out = ADP + phosphate + Ca2+/in
210494, 210473, 210481, 210483, 210489, 210491, 719962, 210476, 210480, 210486, 720447, 210495, 210474, 210475, 210478, 210490, 210492, 210493, 210496, 210498, 720644, 210485, 210479, 210482, 210477, 210497, 210487, 210488, 720121, 684657, 719980, 720908, 720903, 720281, 719497, 720136, 719888, 719869, 210484
ATP + H2O + Ca2+/out = ADP + phosphate + Ca2+/in
210494, 210473, 210481, 210483, 210489, 210491, 719962, 210476, 210480, 210486, 720447, 210495, 210474, 210475, 210478, 210490, 210492, 210493, 210496, 210498, 720644, 210485, 210479, 210482, 210477, 210497, 210487, 210488, 720121, 684657, 719980, 720908, 720903, 720281, 719497, 720136, 719888, 719869, 210484
ATP + H2O + Ca2+[side 1] + H+[side 2] = ADP + phosphate + Ca2+[side 2] + H+[side 1]
ATP + H2O + Ca2+[side 1] + H+[side 2] = ADP + phosphate + Ca2+[side 2] + H+[side 1]
ATP + H2O + Ca2+[side 1] + H+[side 2] = ADP + phosphate + Ca2+[side 2] + H+[side 1]
ATP + H2O + Ca2+[side 1] + H+[side 2] = ADP + phosphate + Ca2+[side 2] + H+[side 1]
ATP + H2O + Ca2+[side 1] + H+[side 2] = ADP + phosphate + Ca2+[side 2] + H+[side 1]
ATP + H2O + Ca2+[side 1] + H+[side 2] = ADP + phosphate + Ca2+[side 2] + H+[side 1]
ATP + H2O + Ca2+[side 1] + H+[side 2] = ADP + phosphate + Ca2+[side 2] + H+[side 1]
ATP + H2O + Ca2+[side 1] = ADP + phosphate + Ca2+[side 2]
733067, 733416, 734304, 751396, 733277, 733466, 734224, 734517, 735113, 748570, 749980, 750486, 750998, 751700, 752192, 733404, 733790, 750281, 734423, 733829, 750181, 750217, 734940, 751369, 733998, 733830, 749857, 752240, 751803, 734372, 750573, 734209, 734516, 750543, 751099, 762019, 761957, 751094, 734295, 733454, 751523, 751525, 750694, 761208, 735233
ATP + H2O + Ca2+[side 1] = ADP + phosphate + Ca2+[side 2]
733067, 733416, 734304, 751396, 733277, 733466, 734224, 734517, 735113, 748570, 749980, 750486, 750998, 751700, 752192, 733404, 733790, 750281, 734423, 733829, 750181, 750217, 734940, 751369, 733998, 733830, 749857, 752240, 751803, 734372, 750573, 734209, 734516, 750543, 751099, 762019, 761957, 751094, 734295, 733454, 751523, 751525, 750694, 761208, 735233
ATP + H2O + Ca2+[side 1] = ADP + phosphate + Ca2+[side 2]
733067, 733416, 734304, 751396, 733277, 733466, 734224, 734517, 735113, 748570, 749980, 750486, 750998, 751700, 752192, 733404, 733790, 750281, 734423, 733829, 750181, 750217, 734940, 751369, 733998, 733830, 749857, 752240, 751803, 734372, 750573, 734209, 734516, 750543, 751099, 762019, 761957, 751094, 734295, 733454, 751523, 751525, 750694, 761208, 735233
ATP + H2O + Ca2+[side 1] = ADP + phosphate + Ca2+[side 2]
733067, 733416, 734304, 751396, 733277, 733466, 734224, 734517, 735113, 748570, 749980, 750486, 750998, 751700, 752192, 733404, 733790, 750281, 734423, 733829, 750181, 750217, 734940, 751369, 733998, 733830, 749857, 752240, 751803, 734372, 750573, 734209, 734516, 750543, 751099, 762019, 761957, 751094, 734295, 733454, 751523, 751525, 750694, 761208, 735233
ATP + H2O + Ca2+[side 1] = ADP + phosphate + Ca2+[side 2]
733067, 733416, 734304, 751396, 733277, 733466, 734224, 734517, 735113, 748570, 749980, 750486, 750998, 751700, 752192, 733404, 733790, 750281, 734423, 733829, 750181, 750217, 734940, 751369, 733998, 733830, 749857, 752240, 751803, 734372, 750573, 734209, 734516, 750543, 751099, 762019, 761957, 751094, 734295, 733454, 751523, 751525, 750694, 761208, 735233
ATP + H2O + Ca2+[side 1] = ADP + phosphate + Ca2+[side 2]
733067, 733416, 734304, 751396, 733277, 733466, 734224, 734517, 735113, 748570, 749980, 750486, 750998, 751700, 752192, 733404, 733790, 750281, 734423, 733829, 750181, 750217, 734940, 751369, 733998, 733830, 749857, 752240, 751803, 734372, 750573, 734209, 734516, 750543, 751099, 762019, 761957, 751094, 734295, 733454, 751523, 751525, 750694, 761208, 735233
ATP + H2O + Ca2+[side 1] = ADP + phosphate + Ca2+[side 2]
733067, 733416, 734304, 751396, 733277, 733466, 734224, 734517, 735113, 748570, 749980, 750486, 750998, 751700, 752192, 733404, 733790, 750281, 734423, 733829, 750181, 750217, 734940, 751369, 733998, 733830, 749857, 752240, 751803, 734372, 750573, 734209, 734516, 750543, 751099, 762019, 761957, 751094, 734295, 733454, 751523, 751525, 750694, 761208, 735233
Product in Enzyme-catalyzed Reactions (92 results)
EC NUMBER
REACTION
REACTION DIAGRAM
LITERATURE
ENZYME 3D STRUCTURE
ATP + H2O + Ca2+/out = ADP + phosphate + Ca2+/in
ATP + H2O + Ca2+/out = ADP + phosphate + Ca2+/in
ATP + H2O + Ca2+/out = ADP + phosphate + Ca2+/in
ATP + H2O + Ca2+/out = ADP + phosphate + Ca2+/in
ATP + H2O + Ca2+/out = ADP + phosphate + Ca2+/in
ATP + H2O + Ca2+/out = ADP + phosphate + Ca2+/in
ATP + H2O + Ca2+/out = ADP + phosphate + Ca2+/in
ATP + H2O + Ca2+[side 1] + H+[side 2] = ADP + phosphate + Ca2+[side 2] + H+[side 1]
ATP + H2O + Ca2+[side 1] + H+[side 2] = ADP + phosphate + Ca2+[side 2] + H+[side 1]
ATP + H2O + Ca2+[side 1] + H+[side 2] = ADP + phosphate + Ca2+[side 2] + H+[side 1]
ATP + H2O + Ca2+[side 1] + H+[side 2] = ADP + phosphate + Ca2+[side 2] + H+[side 1]
ATP + H2O + Ca2+[side 1] + H+[side 2] = ADP + phosphate + Ca2+[side 2] + H+[side 1]
ATP + H2O + Ca2+[side 1] + H+[side 2] = ADP + phosphate + Ca2+[side 2] + H+[side 1]
ATP + H2O + Ca2+[side 1] + H+[side 2] = ADP + phosphate + Ca2+[side 2] + H+[side 1]
Activator in Enzyme-catalyzed Reactions (2586 results)
EC NUMBER
COMMENTARY
LITERATURE
ENZYME 3D STRUCTURE
when the concentration of calcium is increased, calmodulin is released from UBE3B, resulting in an increase in ubiquitylation activity
when the concentration of calcium is increased, calmodulin is released from UBE3B, resulting in an increase in ubiquitylation activity
-
1 mM CaCl2 stimulates 5-O-glucosylation of cyanidin 3-rhamnosyl-glucoside 1.6fold, pH 7.4
-
a Ca2+ concentration of 50-100 mM is optimal for the thermostability of the immobilized CITase, 10-50 mM for the free enzyme
a Ca2+ concentration of 50-100 mM is optimal for the thermostability of the immobilized CITase, 10-50 mM for the free enzyme
a Ca2+ concentration of 50-100 mM is optimal for the thermostability of the immobilized CITase, 10-50 mM for the free enzyme
a Ca2+ concentration of 50-100 mM is optimal for the thermostability of the immobilized CITase, 10-50 mM for the free enzyme
a Ca2+ concentration of 50-100 mM is optimal for the thermostability of the immobilized CITase, 10-50 mM for the free enzyme
a Ca2+ concentration of 50-100 mM is optimal for the thermostability of the immobilized CITase, 10-50 mM for the free enzyme
a Ca2+ concentration of 50-100 mM is optimal for the thermostability of the immobilized CITase, 10-50 mM for the free enzyme
a Ca2+ concentration of 50-100 mM is optimal for the thermostability of the immobilized CITase, 10-50 mM for the free enzyme
activation. In mutants A452N and V744L, activation by Ca2+ is reduced
activation. In mutants A452N and V744L, activation by Ca2+ is reduced
activation. In mutants A452N and V744L, activation by Ca2+ is reduced
activation. In mutants A452N and V744L, activation by Ca2+ is reduced
activation. In mutants A452N and V744L, activation by Ca2+ is reduced
activation. In mutants A452N and V744L, activation by Ca2+ is reduced
activation. In mutants A452N and V744L, activation by Ca2+ is reduced
activation. In mutants A452N and V744L, activation by Ca2+ is reduced
G-protein coupled receptor PAC1 regulates the tyrosine phosphorylation of isoform PYK2 in NCI-H838 nonsmall cell lung cancer cells. PYK2 phosphorylation is dependent upon Ca2+. The ability of PAC1 to regulate PYK2 is dependent on phospholipase and Src, and partially dependent on proteinkinase C
G-protein coupled receptor PAC1 regulates the tyrosine phosphorylation of isoform PYK2 in NCI-H838 nonsmall cell lung cancer cells. PYK2 phosphorylation is dependent upon Ca2+. The ability of PAC1 to regulate PYK2 is dependent on phospholipase and Src, and partially dependent on proteinkinase C
G-protein coupled receptor PAC1 regulates the tyrosine phosphorylation of isoform PYK2 in NCI-H838 nonsmall cell lung cancer cells. PYK2 phosphorylation is dependent upon Ca2+. The ability of PAC1 to regulate PYK2 is dependent on phospholipase and Src, and partially dependent on proteinkinase C
G-protein coupled receptor PAC1 regulates the tyrosine phosphorylation of isoform PYK2 in NCI-H838 nonsmall cell lung cancer cells. PYK2 phosphorylation is dependent upon Ca2+. The ability of PAC1 to regulate PYK2 is dependent on phospholipase and Src, and partially dependent on proteinkinase C
G-protein coupled receptor PAC1 regulates the tyrosine phosphorylation of isoform PYK2 in NCI-H838 nonsmall cell lung cancer cells. PYK2 phosphorylation is dependent upon Ca2+. The ability of PAC1 to regulate PYK2 is dependent on phospholipase and Src, and partially dependent on proteinkinase C
G-protein coupled receptor PAC1 regulates the tyrosine phosphorylation of isoform PYK2 in NCI-H838 nonsmall cell lung cancer cells. PYK2 phosphorylation is dependent upon Ca2+. The ability of PAC1 to regulate PYK2 is dependent on phospholipase and Src, and partially dependent on proteinkinase C
G-protein coupled receptor PAC1 regulates the tyrosine phosphorylation of isoform PYK2 in NCI-H838 nonsmall cell lung cancer cells. PYK2 phosphorylation is dependent upon Ca2+. The ability of PAC1 to regulate PYK2 is dependent on phospholipase and Src, and partially dependent on proteinkinase C
G-protein coupled receptor PAC1 regulates the tyrosine phosphorylation of isoform PYK2 in NCI-H838 nonsmall cell lung cancer cells. PYK2 phosphorylation is dependent upon Ca2+. The ability of PAC1 to regulate PYK2 is dependent on phospholipase and Src, and partially dependent on proteinkinase C
G-protein coupled receptor PAC1 regulates the tyrosine phosphorylation of isoform PYK2 in NCI-H838 nonsmall cell lung cancer cells. PYK2 phosphorylation is dependent upon Ca2+. The ability of PAC1 to regulate PYK2 is dependent on phospholipase and Src, and partially dependent on proteinkinase C
G-protein coupled receptor PAC1 regulates the tyrosine phosphorylation of isoform PYK2 in NCI-H838 nonsmall cell lung cancer cells. PYK2 phosphorylation is dependent upon Ca2+. The ability of PAC1 to regulate PYK2 is dependent on phospholipase and Src, and partially dependent on proteinkinase C
G-protein coupled receptor PAC1 regulates the tyrosine phosphorylation of isoform PYK2 in NCI-H838 nonsmall cell lung cancer cells. PYK2 phosphorylation is dependent upon Ca2+. The ability of PAC1 to regulate PYK2 is dependent on phospholipase and Src, and partially dependent on proteinkinase C
G-protein coupled receptor PAC1 regulates the tyrosine phosphorylation of isoform PYK2 in NCI-H838 nonsmall cell lung cancer cells. PYK2 phosphorylation is dependent upon Ca2+. The ability of PAC1 to regulate PYK2 is dependent on phospholipase and Src, and partially dependent on proteinkinase C
G-protein coupled receptor PAC1 regulates the tyrosine phosphorylation of isoform PYK2 in NCI-H838 nonsmall cell lung cancer cells. PYK2 phosphorylation is dependent upon Ca2+. The ability of PAC1 to regulate PYK2 is dependent on phospholipase and Src, and partially dependent on proteinkinase C
G-protein coupled receptor PAC1 regulates the tyrosine phosphorylation of isoform PYK2 in NCI-H838 nonsmall cell lung cancer cells. PYK2 phosphorylation is dependent upon Ca2+. The ability of PAC1 to regulate PYK2 is dependent on phospholipase and Src, and partially dependent on proteinkinase C
G-protein coupled receptor PAC1 regulates the tyrosine phosphorylation of isoform PYK2 in NCI-H838 nonsmall cell lung cancer cells. PYK2 phosphorylation is dependent upon Ca2+. The ability of PAC1 to regulate PYK2 is dependent on phospholipase and Src, and partially dependent on proteinkinase C
G-protein coupled receptor PAC1 regulates the tyrosine phosphorylation of isoform PYK2 in NCI-H838 nonsmall cell lung cancer cells. PYK2 phosphorylation is dependent upon Ca2+. The ability of PAC1 to regulate PYK2 is dependent on phospholipase and Src, and partially dependent on proteinkinase C
G-protein coupled receptor PAC1 regulates the tyrosine phosphorylation of isoform PYK2 in NCI-H838 nonsmall cell lung cancer cells. PYK2 phosphorylation is dependent upon Ca2+. The ability of PAC1 to regulate PYK2 is dependent on phospholipase and Src, and partially dependent on proteinkinase C
G-protein coupled receptor PAC1 regulates the tyrosine phosphorylation of isoform PYK2 in NCI-H838 nonsmall cell lung cancer cells. PYK2 phosphorylation is dependent upon Ca2+. The ability of PAC1 to regulate PYK2 is dependent on phospholipase and Src, and partially dependent on proteinkinase C
G-protein coupled receptor PAC1 regulates the tyrosine phosphorylation of isoform PYK2 in NCI-H838 nonsmall cell lung cancer cells. PYK2 phosphorylation is dependent upon Ca2+. The ability of PAC1 to regulate PYK2 is dependent on phospholipase and Src, and partially dependent on proteinkinase C
G-protein coupled receptor PAC1 regulates the tyrosine phosphorylation of isoform PYK2 in NCI-H838 nonsmall cell lung cancer cells. PYK2 phosphorylation is dependent upon Ca2+. The ability of PAC1 to regulate PYK2 is dependent on phospholipase and Src, and partially dependent on proteinkinase C
G-protein coupled receptor PAC1 regulates the tyrosine phosphorylation of isoform PYK2 in NCI-H838 nonsmall cell lung cancer cells. PYK2 phosphorylation is dependent upon Ca2+. The ability of PAC1 to regulate PYK2 is dependent on phospholipase and Src, and partially dependent on proteinkinase C
G-protein coupled receptor PAC1 regulates the tyrosine phosphorylation of isoform PYK2 in NCI-H838 nonsmall cell lung cancer cells. PYK2 phosphorylation is dependent upon Ca2+. The ability of PAC1 to regulate PYK2 is dependent on phospholipase and Src, and partially dependent on proteinkinase C
G-protein coupled receptor PAC1 regulates the tyrosine phosphorylation of isoform PYK2 in NCI-H838 nonsmall cell lung cancer cells. PYK2 phosphorylation is dependent upon Ca2+. The ability of PAC1 to regulate PYK2 is dependent on phospholipase and Src, and partially dependent on proteinkinase C
G-protein coupled receptor PAC1 regulates the tyrosine phosphorylation of isoform PYK2 in NCI-H838 nonsmall cell lung cancer cells. PYK2 phosphorylation is dependent upon Ca2+. The ability of PAC1 to regulate PYK2 is dependent on phospholipase and Src, and partially dependent on proteinkinase C
G-protein coupled receptor PAC1 regulates the tyrosine phosphorylation of isoform PYK2 in NCI-H838 nonsmall cell lung cancer cells. PYK2 phosphorylation is dependent upon Ca2+. The ability of PAC1 to regulate PYK2 is dependent on phospholipase and Src, and partially dependent on proteinkinase C
G-protein coupled receptor PAC1 regulates the tyrosine phosphorylation of isoform PYK2 in NCI-H838 nonsmall cell lung cancer cells. PYK2 phosphorylation is dependent upon Ca2+. The ability of PAC1 to regulate PYK2 is dependent on phospholipase and Src, and partially dependent on proteinkinase C
intraperitoneal administration of 1 mg/kg/day for 14 days, increase in enzyme activity by 53%, no change of total antioxidant status
in presence of fructose-1,6-bisphosphate, activates the native enzyme and recombinant FBPase4.5, not FBPase4.9
in presence of fructose-1,6-bisphosphate, activates the native enzyme and recombinant FBPase4.5, not FBPase4.9
in presence of fructose-1,6-bisphosphate, activates the native enzyme and recombinant FBPase4.5, not FBPase4.9
in presence of fructose-1,6-bisphosphate, activates the native enzyme and recombinant FBPase4.5, not FBPase4.9
for isozyme PDP1c, simultaneous presence of Ca2+ and E2 component of substrate is required
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requirement of all PLCs, the delta isoenzymes are most sensitive to Ca2+
requirement of all PLCs, the delta isoenzymes are most sensitive to Ca2+
requirement of all PLCs, the delta isoenzymes are most sensitive to Ca2+
requirement of all PLCs, the delta isoenzymes are most sensitive to Ca2+
requirement of all PLCs, the delta isoenzymes are most sensitive to Ca2+
requirement of all PLCs, the delta isoenzymes are most sensitive to Ca2+
requirement of all PLCs, the delta isoenzymes are most sensitive to Ca2+
requirement of all PLCs, the delta isoenzymes are most sensitive to Ca2+
requirement of all PLCs, the delta isoenzymes are most sensitive to Ca2+
requirement of all PLCs, the delta isoenzymes are most sensitive to Ca2+
requirement of all PLCs, the delta isoenzymes are most sensitive to Ca2+
requirement of all PLCs, the delta isoenzymes are most sensitive to Ca2+
requirement of all PLCs, the delta isoenzymes are most sensitive to Ca2+
requirement of all PLCs, the delta isoenzymes are most sensitive to Ca2+
requirement of all PLCs, the delta isoenzymes are most sensitive to Ca2+
the enzyme acting on PtdIns is Ca2+-dependent, in contrary to that acting on PtdIns(4,5)P2 which remains active in the presence of 10 mM EGTA
the enzyme acting on PtdIns is Ca2+-dependent, in contrary to that acting on PtdIns(4,5)P2 which remains active in the presence of 10 mM EGTA
the enzyme acting on PtdIns is Ca2+-dependent, in contrary to that acting on PtdIns(4,5)P2 which remains active in the presence of 10 mM EGTA
the enzyme acting on PtdIns is Ca2+-dependent, in contrary to that acting on PtdIns(4,5)P2 which remains active in the presence of 10 mM EGTA
the enzyme acting on PtdIns is Ca2+-dependent, in contrary to that acting on PtdIns(4,5)P2 which remains active in the presence of 10 mM EGTA
the enzyme acting on PtdIns is Ca2+-dependent, in contrary to that acting on PtdIns(4,5)P2 which remains active in the presence of 10 mM EGTA
the enzyme acting on PtdIns is Ca2+-dependent, in contrary to that acting on PtdIns(4,5)P2 which remains active in the presence of 10 mM EGTA
the enzyme acting on PtdIns is Ca2+-dependent, in contrary to that acting on PtdIns(4,5)P2 which remains active in the presence of 10 mM EGTA
the enzyme acting on PtdIns is Ca2+-dependent, in contrary to that acting on PtdIns(4,5)P2 which remains active in the presence of 10 mM EGTA
the enzyme acting on PtdIns is Ca2+-dependent, in contrary to that acting on PtdIns(4,5)P2 which remains active in the presence of 10 mM EGTA
the enzyme acting on PtdIns is Ca2+-dependent, in contrary to that acting on PtdIns(4,5)P2 which remains active in the presence of 10 mM EGTA
the enzyme acting on PtdIns is Ca2+-dependent, in contrary to that acting on PtdIns(4,5)P2 which remains active in the presence of 10 mM EGTA
the enzyme acting on PtdIns is Ca2+-dependent, in contrary to that acting on PtdIns(4,5)P2 which remains active in the presence of 10 mM EGTA
the enzyme acting on PtdIns is Ca2+-dependent, in contrary to that acting on PtdIns(4,5)P2 which remains active in the presence of 10 mM EGTA
the enzyme acting on PtdIns is Ca2+-dependent, in contrary to that acting on PtdIns(4,5)P2 which remains active in the presence of 10 mM EGTA
inhibits the PLD37/18-catalyzed hydrolysis of dibutyroylphosphatidylcholine at basic pH values, but activates the enzyme more than twofold at pH 5.5. Addition of Ca2+ at pH 8.0 increases the transphosphatidylation activity 2.5- and 3.5fold with 5 and 20 mM Ca2+, respectively. At pH 9.0, Ca2+ inhibits both phosphohydrolase and transferase activities with much less inhibition to the latter
inhibits the PLD37/18-catalyzed hydrolysis of dibutyroylphosphatidylcholine at basic pH values, but activates the enzyme more than twofold at pH 5.5. Addition of Ca2+ at pH 8.0 increases the transphosphatidylation activity 2.5- and 3.5fold with 5 and 20 mM Ca2+, respectively. At pH 9.0, Ca2+ inhibits both phosphohydrolase and transferase activities with much less inhibition to the latter