EC Number |
Inhibitors |
Structure |
---|
1.5.1.25 | DELTA1-piperideine 2-carboxylate |
substrate inhibition |
|
1.5.1.25 | S-(2-aminoethyl)-L-cysteine ketimine |
substrate inhibition |
|
1.5.1.25 | 3,5,3'-triiodothyronine |
the enzyme shows strong binding to 3,5,3'-triiodothyronine (T3), the active form of thyroxine |
|
1.5.1.25 | 3,5,3'-triiodothyronine |
the ketimine reductase activity of CRYM is strongly inhibited by the thyroid hormone T3 |
|
1.5.1.25 | 3,5,3'-triiodothyronine |
the ketimine reductase activity of CRYM is strongly inhibited by the thyroid hormone T3, especially at neutral pH, reversible inhibition |
|
1.5.1.25 | more |
the P2C reductase activity is potently inhibited by thyroid hormones |
|
1.5.1.25 | more |
the P2C reductase activity is potently inhibited by thyroid hormones, thyroid hormones and analogues docked into the active site of the crystal structure of human KR, overview |
|