1.5.1.25	3,3',5'-L-triiodothyronine	-	220662	
1.5.1.25	3,5,3'-L-triiodothyronine	-	220663	
1.5.1.25	3,5,3'-triiodothyronine	-	101783	
1.5.1.25	3,5-diiodo-L-tyrosine	-	3597	
1.5.1.25	3,5-L-diiodothyronine	-	262440	
1.5.1.25	4,5-dibromopyrrole-2-carboxylate	-	220660	
1.5.1.25	L-thyroxine	-	1380	
1.5.1.25	L-tyrosine	-	109	
1.5.1.25	picolinate	-	15921	
1.5.1.25	pyrrole-2-carboxylate	-	4860	
1.5.1.25	3,3',5'-L-triiodothyronine	competitive inhibition	220662	
1.5.1.25	3,5,3'-L-triiodothyronine	competitive inhibition	220663	
1.5.1.25	3,5-diiodothyronine	competitive inhibition	21471	
1.5.1.25	L-thyroxine	competitive inhibition	1380	
1.5.1.25	L-tyrosine	competitive inhibition	109	
1.5.1.25	picolinate	competitive inhibition, picolinate is a much poorer inhibitor than pyrrole-2-carboxylate because it does not possess a ring -NH and relies on a relatively weak ring interaction	15921	
1.5.1.25	pyrrole-2-carboxylate	competitive inhibition, pyrrole-2-carboxylate is an effective inhibitor of ketimine reductase/CRYM mainly as a result of the -NH hydrogen bonding to an active site residue	4860	
1.5.1.25	additional information	in silico docking of substrates and inhibitors using ketimine reductase/CRYM cyrstal structure, PDB ID 4BVA, overview	2	
1.5.1.25	Triton X-100	irreversible inactivation	61	
1.5.1.25	3,5-diiodo-L-tyrosine	low competitive inhibition	3597	
1.5.1.25	DELTA1-piperideine 2-carboxylate	substrate inhibition	49519	
1.5.1.25	S-(2-aminoethyl)-L-cysteine ketimine	substrate inhibition	220661	
1.5.1.25	3,5,3'-triiodothyronine	the enzyme shows strong binding to 3,5,3'-triiodothyronine (T3), the active form of thyroxine	101783	
1.5.1.25	3,5,3'-triiodothyronine	the ketimine reductase activity of CRYM is strongly inhibited by the thyroid hormone T3	101783	
1.5.1.25	3,5,3'-triiodothyronine	the ketimine reductase activity of CRYM is strongly inhibited by the thyroid hormone T3, especially at neutral pH, reversible inhibition	101783	
1.5.1.25	additional information	the P2C reductase activity is potently inhibited by thyroid hormones	2	
1.5.1.25	additional information	the P2C reductase activity is potently inhibited by thyroid hormones, thyroid hormones and analogues docked into the active site of the crystal structure of human KR, overview	2