EC Number |
Inhibitors |
Structure |
---|
1.5.1.20 | dihydropteroylhexaglutamate |
- |
|
1.5.1.20 | dihydropteroylpolyglutamate |
- |
|
1.5.1.20 | dihydropteroylpolyglutamate |
most potent inhibitor is dihydropteroylhexaglutamate |
|
1.5.1.20 | folylpolyglutamate |
overview |
|
1.5.1.20 | LY309887 |
i.e. 6R-2,5-thienyl-5,10-dideazatetrahydrofolate monoglutamate |
|
1.5.1.20 | menadione |
inhibits enzyme activity in yeast extracts |
|
1.5.1.20 | Mersalyl |
80% inhibition at 1 mM |
|
1.5.1.20 | methylenetetrahydrofolate |
- |
|
1.5.1.20 | more |
residues essential for enzyme activity: arginine, histidine, tryptophan |
|
1.5.1.20 | more |
vitamin B12 and methionine can repress enzyme biosynthesis |
|