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EC Number
Inhibitors
Commentary
Structure
1.14.11.6
5-Nitrouracil
70% inhibition at 5 mM with thymine as substrate
1.14.11.6
6-Azathymine
94% inhibition at 5 mM with thymine as substrate
1.14.11.6
6-methylthymine
41% inhibition at 5 mM with thymine as substrate
1.14.11.6
6-Methyluracil
18% inhibition at 5 mM with thymine as substrate
1.14.11.6
Ni2+
binding structure with truncated enzyme mutant
1.14.11.6
Uracil
non-competitive inhibitor
1.14.11.6
Uracil
inhibitor of the three reactions, 50% inhibition at 1 mM
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