EC Number   |
Inhibitors |
Structure |
|---|
   1.14.11.6 | 5-Ethynyluracil |
binds covalently to a phenylalanine residue of the enzyme |
   |
| 1.14.11.6 | 5-Ethynyluracil |
mechanism-based inactivator |
|
| 1.14.11.6 | 5-fluorouracil |
linear non-competitive inhibitor |
|
| 1.14.11.6 | 5-Formyluracil |
competitive inhibitor with respect to thymine |
|
| 1.14.11.6 | 5-Formyluracil |
79% inhibition at 2.5 mM with thymine as substrate |
|
| 1.14.11.6 | 5-Formyluracil |
competitive inhibitor with respect to 5-hydroxymethyluracil; competitive inhibitor with respect to thymine |
|
| 1.14.11.6 | 5-Hydroxymethyluracil |
competitive inhibitor against thymine, noncompetitive against oxygen |
|
| 1.14.11.6 | 5-Hydroxyuracil |
92% inhibition at 5 mM with thymine as substrate |
|
| 1.14.11.6 | 5-Mercaptouracil |
60% inhibition at 5 mM with thymine as substrate |
|
| 1.14.11.6 | 5-methylaminouracil |
100% inhibition at 5 mM with thymine as substrate |
|
