EC Number |
Activating Compound |
Reference |
---|
5.3.4.1 | calnexin |
interacts with the enzyme via the b and b' domains, binding site and structure, overview |
682877 |
5.3.4.1 | cCMP |
- |
682240 |
5.3.4.1 | dichlorophenyl-1,1-dimethylurea |
blocks the reduction of plastoquinone, resulting in 1.5- to 2fold increase in PDI content |
691172 |
5.3.4.1 | DsbA |
disulfide bond formation is catalyzed by the DsbA/DsbB system, DsbA is critical for catalyzing disulfide bond formation in proteins in the bacterial periplasm, which it accomplishes by directly oxidizing substrate proteins via dithiol-disulfide exchange, DsbA donates its disulfide bond directly to substrate proteins, in the process of transferring electrons from DsbA to a tightly bound ubiquinone cofactor, DsbA must be reoxidized by an electron acceptor, overview |
680746 |
5.3.4.1 | DTT |
absolutely required for activity |
662348 |
5.3.4.1 | DTT |
required for activity |
662327, 662413 |
5.3.4.1 | DTT |
the disulfide reduction activity of PDI-DTT is reduced |
661029 |
5.3.4.1 | GSH |
- |
678408, 679783, 682240, 747784 |
5.3.4.1 | GSH |
required for activity |
662301, 662335 |
5.3.4.1 | GSSG |
- |
682240 |