EC Number   |
Activating Compound |
Reference  |
|---|
    4.1.1.9 | DL-carnitine |
stimulates |
4845 |
| 4.1.1.9 | phosphate |
activates |
4845 |
| 4.1.1.9 | iodoacetamide |
malonyl-decarboxylase activity is induced by treatment of fatty acid synthetase with iodoacetamide |
4848 |
| 4.1.1.9 | iodoacetamide |
treatment of fatty acid synthetase with iodoacetamide induces malonyl-CoA decarboxylase activity and impairs the synthetase activity |
4855 |
| 4.1.1.9 | fatty acid |
increases MCD expression in heart and skeletal muscle |
649300 |
| 4.1.1.9 | more |
high-fat feeding, fasting and streptozotocin-induced diabetes increase the plasma concentration of nonesterified fatty acids, with a concomitant increase in both heart and skeletal muscle MCD mRNA |
649300 |
| 4.1.1.9 | WY-14643 |
specifically stimulates the peroxisome proliferator-activated receptor-alpha increasing MCD expression and activity in heart and skeletal muscle |
649300 |
| 4.1.1.9 | Alkaline phosphatase |
treatment with alkaline phosphatase enhances MCD activity suggesting phosphorylation-related control of enzyme |
649690 |
| 4.1.1.9 | more |
MCD activity is elevated under conditions in which hepatic fatty acid oxidation is known to increase, such as streptozotocin-induced diabetes or following a 48 h fast, 2fold increase in expression in streptozotocin-diabetic rats compared with controls |
649690 |
| 4.1.1.9 | fenofibrate |
increases hepatic mRNA expression and MCD activity |
649775 |
