EC Number   |
Activating Compound |
Reference  |
|---|
   1.2.1.36 | glutathione |
reduced form, reaction rate is maximal, with reduced glutathione |
390263 |
| 1.2.1.36 | apoCRABP |
stimulates retinoic acid synthesis by about 30-50% |
390265 |
| 1.2.1.36 | CRBP |
enzyme recognizes retinal as substrate in presence of CRBP |
390270 |
| 1.2.1.36 | CRBP |
facilitates conversion of retinal into retinoic acid |
390277 |
| 1.2.1.36 | cholecalciferol |
0.2 mM, activation to 136% of the control |
655432 |
| 1.2.1.36 | cholesterol |
- |
673325 |
| 1.2.1.36 | more |
22(R)-hydroxy cholesterol elevates significantly the RALDH2 mRNA level in H2.35 cells |
673325 |
| 1.2.1.36 | more |
dexamethasone, little effect on RALDH expression |
673325 |
| 1.2.1.36 | more |
oxysterols, cholesterol metabolites, induce the RALDH1 gene via upregulation of sterol regulatory element binding protein-1c, SREBP-1c |
673325 |
| 1.2.1.36 | more |
oxysterols, cholesterol metabolites, induce the RALDH2 gene via upregulation of sterol regulatory element binding protein-1c, SREBP-1c |
673325 |
