EC Number   |
Activating Compound |
Reference |
|---|
    1.14.14.18 | 2,4,6-Trinitrobenzene sulfonic acid |
induces HO-1 expression in the colon and stimulates its catalytic activity |
686565 |
| 1.14.14.18 | 5-aminosalicylic acid |
induces HO-1 expression in the colon and stimulates its catalytic activity |
686565 |
| 1.14.14.18 | ascorbate |
addition of a second electron donor like ascorbate leads to 10times faster heme conversion |
702147 |
| 1.14.14.18 | brazilin |
main constituent of Caesalpinia sappan, induces HO-1 expression in a concentration-dependent manner at 0.01-0.3 mM at the level of protein synthesis, thus without affecting mRNA transcription of HO-1 |
704854 |
| 1.14.14.18 | Calmodulin |
calcium-dependent binding to enzyme, 3fold increase in catalytic activity |
659364 |
| 1.14.14.18 | Co protoporphyrin IX |
activates and induces HO-1 |
684348 |
| 1.14.14.18 | Co-protoporphyrin |
- |
688500 |
| 1.14.14.18 | cobalt protoporphyrin IX |
1 mg/kg, 5.9fold increase of activity |
674047 |
| 1.14.14.18 | cobalt protoporphyrin IX chloride |
Copp, a HO-1 activator |
688156 |
| 1.14.14.18 | cysteine |
0.1 mM, slight stimulation, inhibition at 1 mM |
438243 |
