EC Number   |
Activating Compound |
Reference |
|---|
   1.14.13.8 | 2-mercaptoethanolamine |
1 mM |
394698 |
| 1.14.13.8 | cholate |
29% activation at 0.5% concentration |
672958 |
| 1.14.13.8 | cholate |
activates activity of mutant N413K by 23% |
703409 |
| 1.14.13.8 | cysteine |
1 mM |
394698 |
| 1.14.13.8 | Emulgen 913 |
350% activation at 0.2%, 47% activation at 1.0% concentration |
672958 |
| 1.14.13.8 | Guanidines |
stimulate NADPH- and O2-dependent oxidation of tertiary amines and sulfur-containing substrates with alkyl side-chains of less than 5 carbons |
348487 |
| 1.14.13.8 | Lipophilic primary alkylamines |
stimulate NADPH- and O2-dependent oxidation of tertiary amines and sulfur-containing substrates with alkyl side-chain of less than 5 carbons |
348487 |
| 1.14.13.8 | more |
FMO is not induced by xenobiotics |
676315 |
| 1.14.13.8 | more |
FMO is not induced or readily inhibited by drugs in general in contrast to cytochrome P450 monooxygenases |
671729 |
| 1.14.13.8 | more |
FMO1 expression is increased in the myocardial tissue of patients with atrial fibrillation |
690175 |
