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BTO (BRENDA Tissue Ontology)

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Change ontology: Version 2021-10-23

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Tissue

Details for M2 macrophage

M2 macrophage

BTO (BRENDA Tissue Ontology) ID

BTO:0006111

Definition

Macrophages that decrease inflammation and encourage tissue repair. M2 is the phenotype of resident tissue macrophages, and can be further elevated by IL-4. M2 macrophages produce high levels of IL-10, TGF-beta and low levels of IL-12. Tumor-associated macrophages are mainly of the M2 phenotype, and seem to actively promote tumor growth

Synonyms

1. alternatively activated macrophage

References

1. Wikipedia: The Free Encyclopedia

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derives from the parent element

at least 1 tissue/ enzyme/ localization link in this branch

tissue/ enzyme/ localization link to BRENDA

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tissues, cell types and enzyme sources

tissues, cell types and enzyme sources is a

animal

whole body is a

body wall

cardiovascular system part of

connective tissue part of

embryonic structure is a

gland

head

hematopoietic system part of

blood

arterial blood is a

blast cell part of

hematopoietic stem cell derives from

immune stem cell derives from

leukemic stem cell derives from

lymphoid progenitor cell derives from

myeloid progenitor cell derives from

marrow cell derives from

erythroblast is a

megakaryocyte is a

mononuclear phagocyte is a

monocyte

macrophage derives from

alveolar macrophage is a

bone marrow-derived macrophage is a

epitheloid cell derives from

foreign-body giant cell derives from

histiocyte is a

interstitial macrophage is a

Langerhans cell is a

Langhans giant cell is a

M1 macrophage is a

M2 macrophage is a

macrophage cell line derives from

ANA-1 cell is a

BMA cell

BMC-2 cell is a

HD-11 cell is a

J-774 cell is a

RAW-264.7 cell is a

M9A cell

RAW/LR5 cell is a

peritoneal macrophage is a

splenocyte is a

premonocyte is a

myeloid cell line derives from

normoblast is a

polymorphonuclear leukocyte is a

promyelocyte is a

blood clot derives from

blood plasma part of

granuloma cell

hematopoietic cell part of

peripheral blood part of

venous blood is a

hemolymph

hemolymph vessel part of

lymph

lymph vessel part of

lymphoid tissue part of

reticuloendothelial system part of

serum

immune system part of

integument part of

limb

muscular system part of

nervous system part of

pacemaker cell part of

pluripotent stem cell part of

primary cell part of

respiratory system part of

sense organ part of

skeletal system part of

soft body part part of

trunk

urogenital system part of

viscus

fungus

organism form is a

other source is a

plant