BTO (BRENDA Tissue Ontology) ID
BTO:0005597
Definition
Langhans giant cells are large cells found in granulomatous conditions. They are formed by the fusion of epithelioid cells (macrophages), and contain nuclei arranged in a horseshoe-shaped pattern in the cell periphery. Although traditionally their presence was associated with tuberculosis, they are not specific for tuberculosis or even for mycobacterial disease. In fact, they are found in nearly every form of granulomatous disease, regardless of etiology
Synonyms
1. Pirogov-Langhans cell
References
1. Wikipedia: The Free Encyclopedia
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