4.2.3.12Gene ontology ID
GO:0003874
Definition
Catalysis of the reaction: 7,8-dihydroneopterin 3'-triphosphate = 6-pyruvoyl-5,6,7,8-tetrahydropterin + H(+) + triphosphate
Synonyms
1. 2-amino-4-oxo-6-[(1S,2R)-1,2-dihydroxy-3-triphosphooxypropyl]-7,8-dihydroxypteridine triphosphate lyase activity
2. 2-amino-4-oxo-6-[(1S,2R)-1,2-dihydroxy-3-triphosphooxypropyl]-7,8-dihydroxypteridine triphosphate-lyase (6-pyruvoyl-5,6,7,8-tetrahydropterin-forming)
3. 6-pyruvoyl tetrahydrobiopterin synthase activity
4. PTPS activity
References
1. EC 4.2.3.122. RHEA: 22048
3. KEGG REACTION: R04286
4. MetaCyc 4.2.3.12-RXN5. Reactome: R-HSA-1474184 "DHNTP is dephosphorylated by PTPS to PTHP"
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