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Gene ontology
Version 2014-12-22
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Details for alpha-N-acetylgalactosaminide alpha-2,6-sialyltransferase activity
2.4.99.3
Gene ontology ID
GO:0001665
Definition
Catalysis of the reaction: CMP-N-acetylneuraminate + glycano-(1->3)-(N-acetyl-alpha-D-galactosaminyl)-glycoprotein = CMP + glycano-[(2->6)-alpha-N-acetylneuraminyl]-(N-acetyl-D-galactosaminyl)-glycoprotein
Synonyms
1. CMP-N-acetylneuraminate:glycano-1,3-(N-acetyl-alpha-D-galactosaminyl)-glycoprotein alpha-2,6-N-acetylneuraminyltransferase activity
2. GalNAc alpha-2,6-sialyltransferase I activity
References
1. EC 2.4.99.3
2. MetaCyc 2.4.99.3-RXN
3. Reactome: R-HSA-4084980 "ST6GALNAC1-6 transfer Neu5Ac to terminal GalNAc (alpha-2,6 link)"
4. Reactome: R-HSA-9603991 "ST6GALNAC6 transfers Neu5Ac to Type 1 MSGG to form Type 1 DSGG"
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