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Information on EC 2.4.99.3 - alpha-N-acetylgalactosaminide alpha-2,6-sialyltransferase

for references in articles please use BRENDA:EC2.4.99.3
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IUBMB Comments
alpha-N-Acetylgalactosamine linked to threonine or serine is also an acceptor, when substituted at the 3-position.
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The enzyme appears in viruses and cellular organisms
Synonyms
alpha-2,6-ST, alpha-N-acetylgalactosaminylprotein alpha2-->6 sialyltransferase, alpha2,6-sialyltransferase, alpha2,6-sialyltransferase II, CMP-N-acetylneuraminate:alpha-N-acetylgalactosaminide alpha2-->6 sialyltransferase, CMP-Neu5Ac: RGalNAcalpha1-O-Ser/Thralpha2,6-sialyltransferase, CMP-Neu5Ac:GalNAc alpha2,6-sialyltransferase, CMP-NeuAc:galactoside (alpha2-6)-sialyltransferase, CMP-sialic acid:alpha-N-acetylgalactosaminide(R-->Galbeta1-->3GalNAcalpha1-->O-Ser/Thr) alpha2-->6 sialyltransferase, CMPNeu5Ac:GalNAalpha2,6-sialyltransferase, more
REACTION
REACTION DIAGRAM
COMMENTARY hide
ORGANISM
UNIPROT
LITERATURE
CMP-N-acetylneuraminate + glycano-(1->3)-(N-acetyl-alpha-D-galactosaminyl)-glycoprotein = CMP + glycano-[(2->6)-alpha-N-acetylneuraminyl]-(N-acetyl-D-galactosaminyl)-glycoprotein
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PATHWAY SOURCE
PATHWAYS
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