Reference on EC 6.1.1.5 - isoleucine-tRNA ligase and Organism(s) Staphylococcus aureus and UniProt Accession P41368
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AUTHORS
TITLE
JOURNAL
VOL.
PAGES
YEAR
ORGANISM (UNIPROT)
PUBMED ID
SOURCE
Crasto, C.F.; Forrest, A.K.; Karoli, T.; March, D.R.; Mensah, L.; O'Hanlon, P.J.; Nairn, M.R.; Oldham, M.D.; Yue, W.; Banwell, M.G.; Easton, C.J.
Synthesis and activity of analogues of the isoleucyl tRNA synthetase inhibitor SB-203207
Bioorg. Med. Chem.
11
2687-2694
2003
Staphylococcus aureus, Rattus norvegicus, Staphylococcus aureus WCUH29
Pope, A.J.; Lapointe, J.; Mensah, L.; Benson, N.; Brown, M.J.; Moore, K.J.
Characterization of isoleucyl-tRNA synthetase from Staphylococcus aureus. I: Kinetic mechanism of the substrate activation reaction studied by transient and steady-state techniques
J. Biol. Chem.
273
31680-31690
1998
Staphylococcus aureus
Pope, A.J.; Moore, K.J.; McVey, M.; Mensah, L.; Benson, N.; Osbourne, N.; Broom, N.; Brown, M.J.; O'Hanlon, P.
Characterization of isoleucyl-tRNA synthetase from Staphylococcus aureus. II. Mechanism of inhibition by reaction intermediate and pseudomonic acid analogues studied using transient and steady-state kinetics
J. Biol. Chem.
273
31691-31701
1998
Staphylococcus aureus
Pope, A.J.; McVey, M.; Fantom, K.; Moore, K.J.
Effects of substrate and inhibitor binding on proteolysis of isoleucyl-tRNA synthetase from Staphylococcus aureus
J. Biol. Chem.
273
31702-31706
1998
Staphylococcus aureus
Nakama, T.; Nureki, O.; Yokoyama, S.
Structural basis for the recognition of isoleucyl-adenylate and an antibiotic, mupirocin, by isoleucyl-tRNA synthetase
J. Biol. Chem.
276
47387-47393
2001
Staphylococcus aureus (P41368), Staphylococcus aureus, Thermus thermophilus, Thermus thermophilus HB8 / ATCC 27634 / DSM 579
Silvian, L.F.; Wang, J.; Steitz, T.A.
Insights into editing from an Ile-tRNA synthetase structure with tRNAIle and mupirocin
Science
285
1074-1077
1999
Staphylococcus aureus (P41972), Staphylococcus aureus
Yang, J.A.; Park, D.W.; Sohn, J.W.; Yang, I.S.; Kim, K.H.; Kim, M.J.
Molecular analysis of isoleucyl-tRNA synthetase mutations in clinical isolates of methicillin-resistant Staphylococcus aureus with low-level mupirocin resistance
J. Korean Med. Sci.
21
827-832
2006
Staphylococcus aureus (P41972), Staphylococcus aureus
De Pascale, G.; Lloyd, A.J.; Schouten, J.A.; Gilbey, A.M.; Roper, D.I.; Dowson, C.G.; Bugg, T.D.
Kinetic characterisation of lipid II-Ala:alanyl tRNA ligase (MurN) from Streptococcus pneumoniae using semi-synthetic aminoacyl-lipid II substrates
J. Biol. Chem.
283
34571-34579
2008
Staphylococcus aureus
