Reference on EC 6.1.1.1 - tyrosine-tRNA ligase and Organism(s) Geobacillus stearothermophilus and UniProt Accession P00952
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AUTHORS
TITLE
JOURNAL
VOL.
PAGES
YEAR
ORGANISM (UNIPROT)
PUBMED ID
SOURCE
Bhat, T.N.; Blow, D.M.; Brick, P.
Tyrosyl-tRNA synthetase forms a mononucleotide-binding old
J. Mol. Biol.
158
699-709
1982
Geobacillus stearothermophilus
Jones, D.H.; McMillan, A.J.; Fersht, A.R.
Reversible dissociation of dimeric tyrosyl-tRNA synthetase by mutagenesis at the subunit interface
Biochemistry
24
5852-5857
1985
Geobacillus stearothermophilus
Brown, K.A.; Vrielink, A.; Blow, D.M.
Crystal structure of two factitious mutants of tyrosyl-tRNA synthetase
Biochem. Soc. Trans.
14
1228-1229
1985
Geobacillus stearothermophilus
-
Ward, W.H.J.; Fersht, A.R.
Asymmetry of tyrosyl-tRNA synthetase in solution
Biochemistry
27
1041-1049
1988
Geobacillus stearothermophilus
Ward, W.H.J.; Fersht, A.R.
Tyrosyl-tRNA synthetase acts as an asymetric dimer in charging tRNA. A rationale for half-of-the-sites activity
Biochemistry
27
5525-5530
1988
Geobacillus stearothermophilus
Reid, B.R.; Koch, G.L.E.; Boulanger, Y.; Hartley, B.S.; Blow, D.M.
Crystallization and preliminary X-ray diffraction studies on tyrosyl-transfer RNA synthetase from Bacillus stearothermophilus
J. Mol. Biol.
80
199-201
1973
Geobacillus stearothermophilus
Avis, J.M.; Day, A.G.; Garcia, G.A.; Fersht, A.R.
Reaction of modified and unmodified tRNATyr substrates with tyrosyl-tRNA synthetase (Bacillus stearothermophilus)
Biochemistry
32
5312-5320
1993
Geobacillus stearothermophilus
First, E.A.; Fersht, A.R.
Involvement of threonine 234 in catalysis of threonyl adenylate formation by tyrosyl-tRNA synthetase
Biochemistry
32
13644-13650
1993
Geobacillus stearothermophilus
First, E.A.; Fersht, A.R.
Mutation of lysine 233 to alanine introduces positive cooperativity into tyrosyl-tRNA synthetase
Biochemistry
32
13651-13657
1993
Geobacillus stearothermophilus
First, E.A.; Fersht, A.R.
Mutational and kinetic analysis of a mobile loop in tyrosyl-tRNA synthetase
Biochemistry
32
13658-13663
1993
Geobacillus stearothermophilus
Wells, T.N.C.; Knill-Jones, J.W.; Gray, T.E.; Fersht, A.R.
Kinetic and thermodynamic properties of wild-type and engineered mutants of tyrosyl-tRNA synthetase analyzed by pyrophosphate exchange kinetics
Biochemistry
30
5151-5156
1991
Geobacillus stearothermophilus
Fothergill, M.D.; Fersht, A.R.
Correlations between kinetics and X-ray analyses of engineered enzymes - crystal structures of mutants Cys-->Gly35 and Tyr-->Phe34 of tyrosyl-tRNA synthetase
Biochemistry
30
5157-5164
1991
Geobacillus stearothermophilus
First, E.; Fersht, A.R.
Analysis of the role of the KMSKS loop in the catalytic mechanism of the tyrosyl-tRNA synthetase using multimutant cycles
Biochemistry
34
5030-5043
1995
Geobacillus stearothermophilus
Garcia, G.A.; Leatherbarrow, R.J.; Eckstein, F.; Fersht, A.R.
Metal ion dependence of phosphorothioate ATP analogues in the Bacillus stearothermophilus tyrosyl-tRNA synthetase reaction
Biochemistry
29
1643-1648
1990
Geobacillus stearothermophilus
De Prat, G.; Duckworth, H.W.; Fersht, A.R.
Modification of amino acid specificity of tyrosyl-tRNA synthetase by protein engineering
FEBS Lett.
318
167-171
1993
Geobacillus stearothermophilus
Koch, G.L.E.
Tyrosyl transfer ribonucleic acid synthetase from Bacillus stearothermophilus. Preparation and properties of the crystallizable enzyme
Biochemistry
13
2307-2312
1974
Geobacillus stearothermophilus
Irwin, M.J.; Nyborg, J.; Reid, B.R.; Blow, D.M.
The crystal structure of tyrosyl-transfer RNA synthetase at 2.7 A resolution
J. Mol. Biol.
105
577-586
1976
Geobacillus stearothermophilus
Monteilhet, C.; Blow, D.M.
Binding of tyrosine, adenosine triphosphate and analogues to crystalline tyrosyl transfer RNA synthetase
J. Mol. Biol.
122
407-417
1978
Geobacillus stearothermophilus
Airas, R.K.
Chloride affects the interaction between tyrosyl-tRNA synthetase and tRNA
Biochim. Biophys. Acta
1472
51-61
1999
Geobacillus stearothermophilus, Escherichia coli
Brown, P.; Richardson, C.M.; Mensah, L.M.; O'Hanlon, P.J.; Osborne, N.F.; Pope, A.J.; Walker, G.
Molecular recognition of tyrosinyl adenylate analogues by prokaryotic tyrosyl tRNA synthetases
Bioorg. Med. Chem.
7
2473-2485
1999
Geobacillus stearothermophilus, Staphylococcus aureus
Park, Y.C.; Bedouelle, H.
Dimeric tyrosyl-tRNA synthetase from Bacillus stearothermophilus unfolds through a monomeric intermediate. A quantitative analysis under equilibrium conditions
J. Biol. Chem.
273
18052-18059
1998
Geobacillus stearothermophilus
Austin, J.; First, E.A.
Comparison of the catalytic roles played by the KMSKS motif in the human and Bacillus stearothermophilus trosyl-tRNA synthetases
J. Biol. Chem.
277
28394-28399
2002
Geobacillus stearothermophilus, Homo sapiens
Xin, Y.; Li, W.; First, E.A.
Stabilization of the transition state for the transfer of tyrosine to tRNATyr by tyrosyl-tRNA synthetase
J. Mol. Biol.
303
299-310
2000
Geobacillus stearothermophilus
Sharma, G.; First, E.
Thermodynamic analysis reveals a temperature-dependent change in the catalytic mechanism of Bacillus stearothermophilus tyrosyl-tRNA synthetase
J. Biol. Chem.
284
4179-4190
2009
Geobacillus stearothermophilus
