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Information on EC 5.3.1.28 - D-sedoheptulose-7-phosphate isomerase

for references in articles please use BRENDA:EC5.3.1.28

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IUBMB Comments

In Gram-negative bacteria the enzyme is involved in biosynthesis of ADP-L-glycero-β-D-manno-heptose, which is utilized for assembly of the lipopolysaccharide inner core. In Gram-positive bacteria the enzyme is involved in biosynthesis of GDP-D-glycero-α-D-manno-heptose, which is required for assembly of S-layer glycoprotein.

The expected taxonomic range for this enzyme is: Bacteria, Eukaryota, Archaea

Synonyms
phosphoheptose isomerase, hp0857, sedoheptulose-7-phosphate isomerase, sedoheptulose 7-phosphate isomerase, more

REACTION
REACTION DIAGRAM
COMMENTARY hide
ORGANISM
UNIPROT
LITERATURE
D-sedoheptulose 7-phosphate = D-glycero-D-manno-heptose 7-phosphate
show the reaction diagram
PATHWAY SOURCE
PATHWAYS
MetaCyc
ADP-L-glycero-beta-D-manno-heptose biosynthesis, GDP-D-glycero-alpha-D-manno-heptose biosynthesis
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