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Literature summary for 5.3.1.28 extracted from

  • Kneidinger, B.; Marolda, C.; Graninger, M.; Zamyatina, A.; McArthur, F.; Kosma, P.; Valvano, M.A.; Messner, P.
    Biosynthesis pathway of ADP-L-glycero-beta-D-manno-heptose in Escherichia coli (2002), J. Bacteriol., 184, 363-369.
    View publication on PubMedView publication on EuropePMC
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Natural Substrates/ Products (Substrates)

Natural Substrates Organism Comment (Nat. Sub.) Natural Products Comment (Nat. Pro.) Rev. Reac.
D-sedoheptulose 7-phosphate Escherichia coli synthesis of ADP-D-beta-D-heptose in Escherichia coli requires three proteins, GmhA (sedoheptulose 7-phosphate isomerase), HldE (bifunctional D-beta-D-heptose 7-phosphate kinase/D-beta-D-heptose 1-phosphate adenylyltransferase), and GmhB (D,D-heptose 1,7-bisphosphate phosphatase) D-glycero-alpha,beta-D-manno-heptose 7-phosphate
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 ?
D-sedoheptulose 7-phosphate Aneurinibacillus thermoaerophilus
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 D-glycero-D-manno-heptose 7-phosphate
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 ?

Organism

Organism UniProt Comment Textmining
Aneurinibacillus thermoaerophilus Q9AGY7
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Escherichia coli P63224
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Substrates and Products (Substrate)

Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
D-sedoheptulose 7-phosphate
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 Escherichia coli D-glycero-alpha,beta-D-manno-heptose 7-phosphate
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 ?
D-sedoheptulose 7-phosphate synthesis of ADP-D-beta-D-heptose in Escherichia coli requires three proteins, GmhA (sedoheptulose 7-phosphate isomerase), HldE (bifunctional D-beta-D-heptose 7-phosphate kinase/D-beta-D-heptose 1-phosphate adenylyltransferase), and GmhB (D,D-heptose 1,7-bisphosphate phosphatase) Escherichia coli D-glycero-alpha,beta-D-manno-heptose 7-phosphate
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 ?
D-sedoheptulose 7-phosphate
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 Aneurinibacillus thermoaerophilus D-glycero-D-manno-heptose 7-phosphate
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 ?

Synonyms

Synonyms Comment Organism
sedoheptulose 7-phosphate isomerase
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 Aneurinibacillus thermoaerophilus