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(2E,6E)-farnesyl diphosphate
(+)-alpha-santalene + diphosphate
(2E,6E)-farnesyl diphosphate
alpha-santalene + diphosphate
2 (2E,6E)-farnesyl diphosphate
(+)-alpha-santalene + trans-alpha-bergamotene + 2 diphosphate
-
amounts of the sesquiterpenes alpha-santalene and trans-alpha-bergamotene produced are,respectively,1.45 and0.177 mg/l
-
?
additional information
?
-
(2E,6E)-farnesyl diphosphate

(+)-alpha-santalene + diphosphate
-
-
-
?
(2E,6E)-farnesyl diphosphate
(+)-alpha-santalene + diphosphate
-
-
-
?
(2E,6E)-farnesyl diphosphate
(+)-alpha-santalene + diphosphate
when incubated in the presence of 10 mM Mg2+ the enzyme converts (2E,6E)-farnesyl diphosphate into alpha-santalene, beta-santalene and epi-beta-santalene,alpha-exo-bergamotene, as well as traces of alpha-farnesene and beta-farnesene. Incubations with Mn2+ yields mainly alpha-exo-bergamotene
-
-
?
(2E,6E)-farnesyl diphosphate
(+)-alpha-santalene + diphosphate
when incubated in the presence of 10 mM Mg2+ the enzyme converts (2Z,6Z)-farnesyl diphosphate into alpha-endo-bergamotene, alpha-santalene, (Z)-beta-farnesene, epi-beta-santalene and beta-santalene
-
-
?
(2E,6E)-farnesyl diphosphate
(+)-alpha-santalene + diphosphate
-
-
-
?
(2E,6E)-farnesyl diphosphate
(+)-alpha-santalene + diphosphate
when incubated in the presence of 10 mM Mg2+ the enzyme converts (2E,6E)-farnesyl diphosphate into alpha-santalene, beta-santalene and epi-beta-santalene,alpha-exo-bergamotene, as well as traces of alpha-farnesene and beta-farnesene. Incubations with Mn2+ yields mainly alpha-exo-bergamotene
-
-
?
(2E,6E)-farnesyl diphosphate
(+)-alpha-santalene + diphosphate
-
-
-
?
(2E,6E)-farnesyl diphosphate
(+)-alpha-santalene + diphosphate
when incubated in the presence of 10 mM Mg2+ the enzyme converts (2E,6E)-farnesyl diphosphate into alpha-santalene, beta-santalene and epi-beta-santalene,alpha-exo-bergamotene, as well as traces of alpha-farnesene and beta-farnesene. Incubations with Mn2+ yields mainly alpha-exo-bergamotene
-
-
?
(2E,6E)-farnesyl diphosphate

alpha-santalene + diphosphate
-
products are alpha-santalene, beta-, and epi-beta-santalene, exo-alpha-bergamotene, as well as traces of alpha- and beta-farnesene
-
?
(2E,6E)-farnesyl diphosphate
alpha-santalene + diphosphate
-
synthesis of a mixture of sesquiterpenes namely alpha-santalene, beta-santalene, epi-beta-santalene and alpha-bergamotene
-
?
(2E,6E)-farnesyl diphosphate
alpha-santalene + diphosphate
-
products are alpha-santalene, beta-, and epi-beta-santalene, alpha-exo-bergamotene, as well as traces of alpha- and beta-farnesene
-
?
(2E,6E)-farnesyl diphosphate
alpha-santalene + diphosphate
-
products are alpha-santalene, beta-, and epi-beta-santalene, alpha-exo-bergamotene, as well as traces of alpha- and beta-farnesene
-
?
additional information

?
-
the enzyme produces high amonuts of (+)-alpha-santalene from (2E,6E)-farnesyl diphosphate, and traces of (-)-exo-alpha-bergamotene
-
-
?
additional information
?
-
-
the enzyme produces high amonuts of (+)-alpha-santalene from (2E,6E)-farnesyl diphosphate, and traces of (-)-exo-alpha-bergamotene
-
-
?
additional information
?
-
the enzyme produces high amonuts of alpha-santalene from (2E,6E)-farnesyl diphosphate, and traces of (-)-exo-alpha-bergamotene. The enzyme assay is coupled to the inorganic diphosphatase (IPP1) from Saccharomyces cerevisiae. Compound identification and quantification by GC-MS and NMR analysis
-
-
?
additional information
?
-
-
the enzyme produces high amonuts of alpha-santalene from (2E,6E)-farnesyl diphosphate, and traces of (-)-exo-alpha-bergamotene. The enzyme assay is coupled to the inorganic diphosphatase (IPP1) from Saccharomyces cerevisiae. Compound identification and quantification by GC-MS and NMR analysis
-
-
?
additional information
?
-
Santalum album Ssy also accepts (2Z,6Z)-farnesyl diphosphate as substrate, producing a mixture of alpha-endo-bergamotene, alpha-santalene, (Z)-beta-farnesene, epi-beta-santalene, and beta-santalene. With substrate geranyl diphosphate, products are linalool, geraniol, and terpineol along with traces of alpha-pinene and camphene. The product profile resulting from incubations of SaSSy with (E,E)-FPP resembles the authentic essential oil of Santalum album more closely than that of the (Z,Z)-FPP incubations
-
-
?
additional information
?
-
Santalum album Ssy also accepts (2Z,6Z)-farnesyl diphosphate as substrate, producing a mixture of alpha-endo-bergamotene, alpha-santalene, (Z)-beta-farnesene, epi-beta-santalene, and beta-santalene. With substrate geranyl diphosphate, products are linalool, geraniol, and terpineol along with traces of alpha-pinene and camphene
-
-
?
additional information
?
-
the enzyme produces high amounts of (+)-alpha-santalene and (-)-beta-santalene, also (-)-exo-alpha-bergamotene, and low amounts of (-)-epi-beta-santalene from (2E,6E)-farnesyl diphosphate
-
-
?
additional information
?
-
the enzyme produces high amounts of (+)-alpha-santalene and (-)-beta-santalene, also (-)-exo-alpha-bergamotene, and low amounts of (-)-epi-beta-santalene from (2E,6E)-farnesyl diphosphate. The enzyme assay is coupled to the inorganic diphosphatase (IPP1) from Saccharomyces cerevisiae. Compound identification and quantification by GC-MS and NMR analysis
-
-
?
additional information
?
-
Santalum austrocaledonicum Ssy also accepts (2Z,6Z)-farnesyl diphosphate as substrate, producing a mixture of endo-alpha-bergamotene, alpha-santalene, (Z)-beta-farnesene, epi-beta-santalene, and beta-santalene. With substrate geranyl diphosphate, products are linalool, geraniol, and terpineol along with traces of alpha-pinene and camphene
-
-
?
additional information
?
-
Santalum spicatum Ssy also accepts (2Z,6Z)-farnesyl diphosphate as substrate, producing a mixture of endo-alpha-bergamotene, alpha-santalene, (Z)-beta-farnesene, epi-beta-santalene, and beta-santalene. With substrate geranyl diphosphate, products are linalool, geraniol, and terpineol along with traces of alpha-pinene and camphene
-
-
?
additional information
?
-
the enzyme produces (+)-alpha-santalene, (-)-beta-santalene, and (-)-exo-alpha-bergamotene, and traces of (-)-epi-beta-santalene from (2E,6E)-farnesyl diphosphate
-
-
?
additional information
?
-
the enzyme produces high amonuts of (+)-alpha-santalene and (-)-exo-alpha-bergamotene, also (-)-beta-santalene, and traces of (-)-epi-beta-santalene from (2E,6E)-farnesyl diphosphate. The enzyme assay is coupled to the inorganic diphosphatase (IPP1) from Saccharomyces cerevisiae. Compound identification and quantification by GC-MS and NMR analysis
-
-
?
Please wait a moment until the data is sorted. This message will disappear when the data is sorted.
(2E,6E)-farnesyl diphosphate
(+)-alpha-santalene + diphosphate
(2E,6E)-farnesyl diphosphate
alpha-santalene + diphosphate
additional information
?
-
(2E,6E)-farnesyl diphosphate

(+)-alpha-santalene + diphosphate
-
-
-
?
(2E,6E)-farnesyl diphosphate
(+)-alpha-santalene + diphosphate
-
-
-
?
(2E,6E)-farnesyl diphosphate
(+)-alpha-santalene + diphosphate
-
-
-
?
(2E,6E)-farnesyl diphosphate
(+)-alpha-santalene + diphosphate
-
-
-
?
(2E,6E)-farnesyl diphosphate

alpha-santalene + diphosphate
-
products are alpha-santalene, beta-, and epi-beta-santalene, exo-alpha-bergamotene, as well as traces of alpha- and beta-farnesene
-
?
(2E,6E)-farnesyl diphosphate
alpha-santalene + diphosphate
-
products are alpha-santalene, beta-, and epi-beta-santalene, alpha-exo-bergamotene, as well as traces of alpha- and beta-farnesene
-
?
(2E,6E)-farnesyl diphosphate
alpha-santalene + diphosphate
-
products are alpha-santalene, beta-, and epi-beta-santalene, alpha-exo-bergamotene, as well as traces of alpha- and beta-farnesene
-
?
additional information

?
-
the enzyme produces high amonuts of (+)-alpha-santalene from (2E,6E)-farnesyl diphosphate, and traces of (-)-exo-alpha-bergamotene
-
-
?
additional information
?
-
-
the enzyme produces high amonuts of (+)-alpha-santalene from (2E,6E)-farnesyl diphosphate, and traces of (-)-exo-alpha-bergamotene
-
-
?
additional information
?
-
Santalum album Ssy also accepts (2Z,6Z)-farnesyl diphosphate as substrate, producing a mixture of alpha-endo-bergamotene, alpha-santalene, (Z)-beta-farnesene, epi-beta-santalene, and beta-santalene. With substrate geranyl diphosphate, products are linalool, geraniol, and terpineol along with traces of alpha-pinene and camphene. The product profile resulting from incubations of SaSSy with (E,E)-FPP resembles the authentic essential oil of Santalum album more closely than that of the (Z,Z)-FPP incubations
-
-
?
additional information
?
-
the enzyme produces high amounts of (+)-alpha-santalene and (-)-beta-santalene, also (-)-exo-alpha-bergamotene, and low amounts of (-)-epi-beta-santalene from (2E,6E)-farnesyl diphosphate
-
-
?
additional information
?
-
Santalum austrocaledonicum Ssy also accepts (2Z,6Z)-farnesyl diphosphate as substrate, producing a mixture of endo-alpha-bergamotene, alpha-santalene, (Z)-beta-farnesene, epi-beta-santalene, and beta-santalene. With substrate geranyl diphosphate, products are linalool, geraniol, and terpineol along with traces of alpha-pinene and camphene
-
-
?
additional information
?
-
Santalum spicatum Ssy also accepts (2Z,6Z)-farnesyl diphosphate as substrate, producing a mixture of endo-alpha-bergamotene, alpha-santalene, (Z)-beta-farnesene, epi-beta-santalene, and beta-santalene. With substrate geranyl diphosphate, products are linalool, geraniol, and terpineol along with traces of alpha-pinene and camphene
-
-
?
additional information
?
-
the enzyme produces (+)-alpha-santalene, (-)-beta-santalene, and (-)-exo-alpha-bergamotene, and traces of (-)-epi-beta-santalene from (2E,6E)-farnesyl diphosphate
-
-
?
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Mg2+

required for activity
Mg2+
required for activity
Mg2+
when incubated in the presence of 10 mM Mg2+ the enzyme converts (E,E)-farnesyl diphosphate into alpha-santalene, beta-santalene and epi-beta-santalene,alpha-exo-bergamotene, as well as traces of alpha-farnesene and beta-farnesene. Incubations with Mn2+ yields mainly alpha-exo-bergamotene
Mg2+
when incubated in the presence of 10 mM Mg2+ the enzyme converts (E,E)-farnesyl diphosphate into alpha-santalene, beta-santalene and epi-beta-santalene,alpha-exo-bergamotene, as well as traces of alpha-farnesene and beta-farnesene. Incubations with Mn2+ yields mainly alpha-exo-bergamotene
Mg2+
required for activity
Mg2+
when incubated in the presence of 10 mM Mg2+ the enzyme converts (E,E)-farnesyl diphosphate into alpha-santalene, beta-santalene and epi-beta-santalene,alpha-exo-bergamotene, as well as traces of alpha-farnesene and beta-farnesene. Incubations with Mn2+ yields mainly alpha-exo-bergamotene
Mn2+

when incubated in the presence of 10 mM Mg2+ the enzyme converts (E,E)-farnesyl diphosphate into alpha-santalene, beta-santalene and epi-beta-santalene,alpha-exo-bergamotene, as well as traces of alpha-farnesene and beta-farnesene. Incubations with Mn2+ yields mainly alpha-exo-bergamotene
Mn2+
incubation in presence of Mn2+ yields mainly alpha-exo-bergamotene
Mn2+
when incubated in the presence of 10 mM Mg2+ the enzyme converts (E,E)-farnesyl diphosphate into alpha-santalene, beta-santalene and epi-beta-santalene,alpha-exo-bergamotene, as well as traces of alpha-farnesene and beta-farnesene. Incubations with Mn2+ yields mainly alpha-exo-bergamotene
Mn2+
incubation in presence of Mn2+ yields mainly exo-alpha-bergamotene
Mn2+
when incubated in the presence of 10 mM Mg2+ the enzyme converts (E,E)-farnesyl diphosphate into alpha-santalene, beta-santalene and epi-beta-santalene,alpha-exo-bergamotene, as well as traces of alpha-farnesene and beta-farnesene. Incubations with Mn2+ yields mainly alpha-exo-bergamotene
Please wait a moment until the data is sorted. This message will disappear when the data is sorted.
0.0014 - 0.0027
(2E,6E)-farnesyl diphosphate
additional information
additional information
-
0.0014
(2E,6E)-farnesyl diphosphate

30°C, pH 8.0
0.0014
(2E,6E)-farnesyl diphosphate
30°C, pH 8.0
0.0014
(2E,6E)-farnesyl diphosphate
30°C, pH 8.0
0.0014
(2E,6E)-farnesyl diphosphate
pH 7.4, 25°C
0.0014
(2E,6E)-farnesyl diphosphate
pH 7.4, 25°C
0.0014
(2E,6E)-farnesyl diphosphate
pH 7.4, 25°C
0.0015
(2E,6E)-farnesyl diphosphate
recombinant His-tagged enzyme, pH 7.4, 37°C
0.002
(2E,6E)-farnesyl diphosphate
recombinant His-tagged enzyme, pH 7.4, 37°C
0.0027
(2E,6E)-farnesyl diphosphate
recombinant His-tagged enzyme, pH 7.4, 37°C
additional information
additional information

Michaelis-Menten kinetic analysis, overview. Kinetics are measured by IPP1 coupled colorimetric assay
-
additional information
additional information
Michaelis-Menten kinetic analysis, overview. Kinetics are measured by IPP1 coupled colorimetric assay
-
additional information
additional information
Michaelis-Menten kinetic analysis, overview. Kinetics are measured by IPP1 coupled colorimetric assay
-
additional information
additional information
-
Michaelis-Menten kinetic analysis, overview. Kinetics are measured by IPP1 coupled colorimetric assay
-
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Jones, C.G.; Moniodis, J.; Zulak, K.G.; Scaffidi, A.; Plummer, J.A.; Ghisalberti, E.L.; Barbour, E.L.; Bohlmann, J.
Sandalwood fragrance biosynthesis involves sesquiterpene synthases of both the terpene synthase (TPS)-a and TPS-b subfamilies, including santalene synthases
J. Biol. Chem.
286
17445-17454
2011
Santalum album (E3W202), Santalum austrocaledonicum (E3W203), Santalum spicatum (E3W204)
brenda
Rani, A.; Ravikumar, P.; Reddy, M.D.; Kush, A.
Molecular regulation of santalol biosynthesis in Santalum album L.
Gene
527
642-648
2013
Santalum album (K7WTQ7), Santalum album
brenda
Scalcinati, G.; Knuf, C.; Partow, S.; Chen, Y.; Maury, J.; Schalk, M.; Daviet, L.; Nielsen, J.; Siewers, V.
Dynamic control of gene expression in Saccharomyces cerevisiae engineered for the production of plant sesquitepene alpha-santalene in a fed-batch mode
Metab. Eng.
14
91-103
2012
Clausena lansium (E5LLI1)
brenda
Hua, G.; Hu, Y.; Yang, C.; Liu, D.; Mao, Z.; Zhang, L.; Zhang, Y.
Characterization of santalene synthases using an inorganic pyrophosphatase coupled colorimetric assay
Anal. Biochem.
547
26-36
2018
Santalum album (E3W202), Santalum spicatum (E3W204), Clausena lansium (E5LLI1), Clausena lansium
brenda