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Information on EC 4.2.3.7 - pentalenene synthase

for references in articles please use BRENDA:EC4.2.3.7

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IUBMB Comments

Isolated from Streptomyces avermitilis. The enzyme is involved in the biosynthesis of pentalenolactone and related antibiotics. The 9si hydrogen of farnesyl diphosphate undergoes a 1,2-hydride shift where it becomes the 1α hydrogen of pentalenene.

The expected taxonomic range for this enzyme is: Bacteria, Eukaryota

Synonyms
pentalenene synthase, more

REACTION
REACTION DIAGRAM
COMMENTARY hide
ORGANISM
UNIPROT
LITERATURE
(2E,6E)-farnesyl diphosphate = pentalenene + diphosphate
show the reaction diagram
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