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Literature summary for 4.2.3.7 extracted from

  • Seemann, M.; Zhai, G.; Umezawa, K.; Cane, D.
    Pentalenene synthase. Histidine-309 is not required for catalytic activity (1999), J. Am. Chem. Soc., 121, 591-592.
No PubMed abstract available

Protein Variants

Protein Variants Comment Organism
H309A retains enzymatic activity, minor increase in Km-value Streptomyces exfoliatus
H309C retains enzymatic activity, minor increase in Km-value Streptomyces exfoliatus
H309F retains enzymatic activity, minor increase in Km-value Streptomyces exfoliatus
H309S retains enzymatic activity, minor increase in Km-value Streptomyces exfoliatus

KM Value [mM]

KM Value [mM] KM Value Maximum [mM] Substrate Comment Organism Structure
0.0003
-
farnesyl diphosphate 30°C, pH 8.2 Streptomyces exfoliatus

Organism

Organism UniProt Comment Textmining
Streptomyces exfoliatus Q55012
-
-

Substrates and Products (Substrate)

Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
farnesyl diphosphate
-
Streptomyces exfoliatus pentalenene + diphosphate
-
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