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Information on EC 3.5.1.94 - gamma-glutamyl-gamma-aminobutyrate hydrolase

for references in articles please use BRENDA:EC3.5.1.94
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IUBMB Comments
Forms part of a putrescine-utilizing pathway in Escherichia coli, in which it has been hypothesized that putrescine is first glutamylated to form gamma-glutamylputrescine, which is oxidized to 4-(gamma-glutamylamino)butanal and then to 4-(gamma-glutamylamino)butanoate. The enzyme can also catalyse the reactions of EC 3.5.1.35 (D-glutaminase) and EC 3.5.1.65 (theanine hydrolase).
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The expected taxonomic range for this enzyme is: Escherichia coli K-12
Synonyms
PuuD, more
REACTION
REACTION DIAGRAM
COMMENTARY hide
ORGANISM
UNIPROT
LITERATURE
4-(gamma-L-glutamylamino)butanoate + H2O = 4-aminobutanoate + L-glutamate
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