Any feedback?
Please rate this page
(enzyme.php)
(0/150)

BRENDA support

Information on EC 3.4.24.84 - Ste24 endopeptidase

for references in articles please use BRENDA:EC3.4.24.84

Please wait a moment until all data is loaded. This message will disappear when all data is loaded.
IUBMB Comments

Type example of peptidase family M48. One of two enzymes that can catalyse this processing step for mating a-factor in yeast. Subsequently, the S-isoprenylated cysteine residue that forms the new C-terminus is methyl-esterified and forms a hydrophobic membrane-anchor.

The expected taxonomic range for this enzyme is: Eukaryota, Bacteria, Archaea
Reaction Schemes
The peptide bond hydrolysed can be designated -C-/-aaX in which C is an S-isoprenylated cysteine residue, a is usually aliphatic and X is the C-terminal residue of the substrate protein, and may be any of several amino acids

Synonyms
zmpste24, ste24p, face-1, atste24, afc1p, hs ste24p, a-factor converting enzyme, more

REACTION
REACTION DIAGRAM
COMMENTARY hide
ORGANISM
UNIPROT
LITERATURE
The peptide bond hydrolysed can be designated -C-/-aaX in which C is an S-isoprenylated cysteine residue, a is usually aliphatic and X is the C-terminal residue of the substrate protein, and may be any of several amino acids
show the reaction diagram
-
-
-
-
Highest Expressing Human Cell Lines
Cell Line Links Gene Links