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Information on EC 3.2.1.161 - beta-apiosyl-beta-glucosidase

for references in articles please use BRENDA:EC3.2.1.161

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IUBMB Comments

The enzyme from the tropical tree Dalbergia nigrescens Kurz belongs in glycosyl hydrolase family 1. The enzyme removes disaccharides from the natural substrates dalpatein 7-O-β-D-apiofuranosyl-(1→6)-β-D-glucopyranoside and 7-hydroxy-2′,4′,5′,6-tetramethoxy-7-O-β-D-apiofuranosyl-(1→6)-β-D-glucopyranoside (dalnigrein 7-O-β-D-apiofuranosyl-(1→6)-β-D-glucopyranoside) although it can also remove a single glucose residue from isoflavonoid 7-O-glucosides . Daidzin and genistin are also substrates.

The enzyme appears in viruses and cellular organisms

Synonyms
dnbglu2, furcatin hydrolase, more

REACTION
REACTION DIAGRAM
COMMENTARY hide
ORGANISM
UNIPROT
LITERATURE
7-[beta-D-apiofuranosyl-(1->6)-beta-D-glucopyranosyloxy]isoflavonoid + H2O = a 7-hydroxyisoflavonoid + beta-D-apiofuranosyl-(1->6)-D-glucose
show the reaction diagram
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PATHWAY SOURCE
PATHWAYS
MetaCyc
dalpatein and dalnigrein biosynthesis, furcatin degradation
Highest Expressing Human Cell Lines
Cell Line Links Gene Links