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Information on EC - thiamine phosphate phosphatase

for references in articles please use BRENDA:EC3.1.3.100
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EC Tree
     3 Hydrolases
         3.1 Acting on ester bonds
             3.1.3 Phosphoric-monoester hydrolases
       thiamine phosphate phosphatase
IUBMB Comments
The enzyme participates in the thiamine biosynthesis pathway in eukaryotes and a few prokaryotes. These organisms lack EC, thiamine-phosphate kinase, and need to convert thiamine phosphate to thiamine diphosphate, the active form of the vitamin, by first removing the phosphate group, followed by diphosphorylation by EC, thiamine diphosphokinase.
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Word Map
  • tmpase
  • horn
  • gelatinosa
  • transganglionic
  • axoplasmic
  • fluoride-resistant
  • buckwheat
  • pyrophosphokinase
  • 14cthiamine
The expected taxonomic range for this enzyme is: Eukaryota, Bacteria
hydroxyethylthiazole kinase, pho4, PMU3, TDP/TMP phosphatase, thiamin-binding protein, thiamin-repressible acid phosphatase, thiamine monophosphatase, thiamine phosphatase, thiamine phosphate phosphatase, thiamine-(di)phosphate phosphatase, more
thiamine phosphate + H2O = thiamine + phosphate
show the reaction diagram
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