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Information on EC 2.7.7.7 - DNA-directed DNA polymerase and Organism(s) Arabidopsis thaliana and UniProt Accession Q9LVN7

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EC Tree
     2 Transferases
         2.7 Transferring phosphorus-containing groups
             2.7.7 Nucleotidyltransferases
                2.7.7.7 DNA-directed DNA polymerase
IUBMB Comments
Catalyses DNA-template-directed extension of the 3'- end of a DNA strand by one nucleotide at a time. Cannot initiate a chain de novo. Requires a primer, which may be DNA or RNA. See also EC 2.7.7.49 RNA-directed DNA polymerase.
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This record set is specific for:
Arabidopsis thaliana
UNIPROT: Q9LVN7
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Word Map
The taxonomic range for the selected organisms is: Arabidopsis thaliana
The enzyme appears in selected viruses and cellular organisms
Synonyms
dna polymerase alpha, dna polymerase beta, dna polymerase iii, pol beta, klenow fragment, dna polymerase delta, taq dna polymerase, pol delta, pol alpha, dna polymerase gamma, more
SYNONYM
ORGANISM
UNIPROT
COMMENTARY hide
LITERATURE
ABO4/POL2a/TIL1
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deoxynucleate polymerase
-
-
-
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deoxyribonucleate nucleotidyltransferase
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-
-
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deoxyribonucleic acid duplicase
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-
-
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deoxyribonucleic acid polymerase
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-
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deoxyribonucleic duplicase
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-
-
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deoxyribonucleic polymerase
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-
-
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deoxyribonucleic polymerase I
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-
-
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DNA duplicase
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-
-
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DNA nucleotidyltransferase
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-
-
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DNA nucleotidyltransferase (DNA-directed)
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-
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DNA polmerase beta
-
-
-
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DNA polymerase
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-
-
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DNA polymerase alpha
-
-
-
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DNA polymerase delta
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DNA polymerase epsilon
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-
DNA polymerase eta
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DNA polymerase gamma
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-
-
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DNA polymerase I
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-
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DNA polymerase II
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-
-
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DNA polymerase III
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-
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DNA replicase
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-
-
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DNA-dependent DNA polymerase
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-
-
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duplicase
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-
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Klenow fragment
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-
-
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nucleotidyltransferase, deoxyribonucleate
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-
-
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Pol gamma
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-
-
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POL2a
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catalytic subunit of DNA polymerase epsilon
POLdelta1
catalytic subunit of the DNA polymerase delta
sequenase
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-
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Taq DNA polymerase
-
-
-
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Taq Pol I
-
-
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-
Tca DNA polymerase
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-
-
-
REACTION TYPE
ORGANISM
UNIPROT
COMMENTARY hide
LITERATURE
nucleotidyl group transfer
-
-
-
-
SYSTEMATIC NAME
IUBMB Comments
deoxynucleoside-triphosphate:DNA deoxynucleotidyltransferase (DNA-directed)
Catalyses DNA-template-directed extension of the 3'- end of a DNA strand by one nucleotide at a time. Cannot initiate a chain de novo. Requires a primer, which may be DNA or RNA. See also EC 2.7.7.49 RNA-directed DNA polymerase.
CAS REGISTRY NUMBER
COMMENTARY hide
9012-90-2
-
SUBSTRATE
PRODUCT                       
REACTION DIAGRAM
ORGANISM
UNIPROT
COMMENTARY
(Substrate) hide
LITERATURE
(Substrate)
COMMENTARY
(Product) hide
LITERATURE
(Product)
Reversibility
r=reversible
ir=irreversible
?=not specified
deoxynucleoside triphosphate + DNAn
diphosphate + DNAn+1
show the reaction diagram
ACTIVATING COMPOUND
ORGANISM
UNIPROT
COMMENTARY hide
LITERATURE
IMAGE
proliferating cell nuclear antigen
-
interaction with monoubiquitylated proliferating cell nuclear antigen is necessary for biological activity and is required for translesion synthesis past UV photoproducts by Poleta
-
ORGANISM
COMMENTARY hide
LITERATURE
UNIPROT
SEQUENCE DB
SOURCE
GENERAL INFORMATION
ORGANISM
UNIPROT
COMMENTARY hide
LITERATURE
malfunction
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abo4 mutants show early flowering and reduced expression of flowering locus C and increased expression of flowering locus T with changing histone H3 modifications
physiological function
UNIPROT
ENTRY NAME
ORGANISM
NO. OF AA
NO. OF TRANSM. HELICES
MOLECULAR WEIGHT[Da]
SOURCE
SEQUENCE
LOCALIZATION PREDICTION?
DPOD1_ARATH
1095
0
123236
Swiss-Prot
Mitochondrion (Reliability: 5)
PROTEIN VARIANTS
ORGANISM
UNIPROT
COMMENTARY hide
LITERATURE
G534R
-
abscisic acid overly sensitive mutant, also hypersensitive to methyl methanesulfonate and UV-B light
additional information
-
null mutations in Arabidopsis POL2a are embryonic lethal
EXPRESSION
ORGANISM
UNIPROT
LITERATURE
the downregulation of the POLdelta1 transcripts do not require an induction by alcohol
REF.
AUTHORS
TITLE
JOURNAL
VOL.
PAGES
YEAR
ORGANISM (UNIPROT)
PUBMED ID
SOURCE
Schuermann, D.; Fritsch, O.; Lucht, J.M.; Hohn, B.
Replication stress leads to genome instabilities in Arabidopsis DNA polymerase delta mutants
Plant Cell
21
2700-2714
2009
Arabidopsis thaliana (Q9LVN7), Arabidopsis thaliana
Manually annotated by BRENDA team
Yin, H.; Zhang, X.; Liu, J.; Wang, Y.; He, J.; Yang, T.; Hong, X.; Yang, Q.; Gong, Z.
Epigenetic regulation, somatic homologous recombination, and abscisic acid signaling are influenced by DNA polymerase epsilon mutation in Arabidopsis
Plant Cell
21
386-402
2009
Arabidopsis thaliana
Manually annotated by BRENDA team
Kunz, B.A.
A role for PCNA2 in translesion synthesis by Arabidopsis thaliana DNA polymerase eta
Plant Signal. Behav.
3
897-898
2008
Arabidopsis thaliana
Manually annotated by BRENDA team