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2-pyridone-2'-deoxyriboside triphosphate + 5'-TAATACGACTCACTATAGGGAGA-3'
diphosphate + ?
-
-
-
?
4-bromo-2-pyridone-2'-deoxyriboside triphosphate + 5'-TAATACGACTCACTATAGGGAGA-3'
diphosphate + ?
-
-
-
?
4-chloro-2-pyridone-2'-deoxyriboside triphosphate + 5'-TAATACGACTCACTATAGGGAGA-3'
diphosphate + ?
-
-
-
?
4-hydroxy-2-pyridone-2'-deoxyriboside triphosphate + 5'-TAATACGACTCACTATAGGGAGA-3'
diphosphate + ?
-
-
-
?
4-thio-2'-deoxyuridine triphosphate + 5'-TAATACGACTCACTATAGGGAGA-3'
diphosphate + ?
-
-
-
?
5-carboxy-2'-deoxyuridine triphosphate + 5'-TAATACGACTCACTATAGGGAGA-3'
diphosphate + ?
-
-
-
?
5-cyano-2'-deoxyuridine triphosphate + 5'-TAATACGACTCACTATAGGGAGA-3'
diphosphate + ?
-
-
-
?
a 2'-deoxyribonucleoside 5'-triphosphate + DNAn
diphosphate + DNAn+1
-
-
-
?
Cy5-dCTP + 2bA FAM oligo
diphosphate + ?
2bA FAM oligo is a primer with FAM at 2 bases from the 3' end (5'-CGCTTGCACAGGTGCGTT/iFluorT/CA-3')
-
-
?
dCTP + DNAn
diphosphate + DNAn+1
-
-
-
?
d[5-(3-aminophenyl)]CTP + DNA
diphosphate + ?
5-substituted dCTPs give products elongated by 1 to 5 nucleotides, with most intense bands corresponding to 2-3 extra nucleotides
-
-
?
d[5-(3-aminophenyl)]UTP + DNA
diphosphate + ?
5-substituted dUTPs give products elongated by 4 to 5 nucleotides, the maximum length of the tail is about 14 nucleotides
-
-
?
d[5-(3-nitrophenyl)]CTP + DNA
diphosphate + ?
5-substituted dCTPs give products elongated by 1 to 5 nucleotides, with most intense bands corresponding to 2-3 extra nucleotides
-
-
?
d[5-(3-nitrophenyl)]UTP + DNA
diphosphate + ?
5-substituted dUTPs give products elongated by 4 to 5 nucleotides, the maximum length of the tail is about 14 nucleotides
-
-
?
d[7-deaza-7-(3-aminophenyl)]ATP + DNA
diphosphate + ?
the most intense band observed for reaction with 7-deaza,7-substituted dATPs corresponds to one nucleotide attached, but the products are rather polydisperse in lengths, reaching several tens of extra nucleotides
-
-
?
d[7-deaza-7-(3-aminophenyl)]GTP + DNA
diphosphate + ?
-
-
-
?
d[7-deaza-7-(3-nitrophenyl)]ATP + DNA
diphosphate + ?
the most intense band observed for reaction with 7-deaza,7-substituted dATPs corresponds to one nucleotide attached, but the products are rather polydisperse in lengths, reaching several tens of extra nucleotides
-
-
?
d[7-deaza-7-(3-nitrophenyl)]GTP + DNA
diphosphate + ?
most useful substrate, efficiently incorporated by the transferase to form long tail-labels at any oligonucleotide
-
-
?
N4-amino-2'-deoxycytidine triphosphate + 5'-TAATACGACTCACTATAGGGAGA-3'
diphosphate + ?
-
-
-
?
D-beta-deoxythymidine-triphosphate + DNAn
diphosphate + DNAn+1
-
-
-
-
?
dATP + DNAn
diphosphate + DNAn+1
-
-
-
-
?
dATP + poly(dA)50
diphosphate + poly(dA)51
-
-
-
-
?
dCTP + DNAn
diphosphate + DNAn+1
-
-
-
-
?
deoxynucleoside triphosphate + DNA
diphosphate + DNAn+1
deoxynucleoside triphosphate + DNAn
diphosphate + DNAn+1
dGTP + DNA
diphosphate + DNA
-
-
-
-
?
dGTP + DNAn
diphosphate + DNAn+1
-
-
-
-
?
ribonucleoside triphosphate + DNAn
diphosphate + ?
-
-
-
-
?
ssDNA + ferrocene-labeled dideoxy-UTP
ssDNA-ddUFc + diphosphate
-
-
-
-
?
additional information
?
-
deoxynucleoside triphosphate + DNA
diphosphate + DNAn+1
-
hypothesis: terminal transferase acts as a somatic mutator, diversifying the amino acid sequence in the variable region of immunoglobulin molecules by changing one of the nucleotides
-
-
?
deoxynucleoside triphosphate + DNA
diphosphate + DNAn+1
-
enzyme may act as a random-sequence generator in highly localized regions of the DNA, enzyme may be an intracellular marker for a subpopulation of cells
-
-
?
deoxynucleoside triphosphate + DNA
diphosphate + DNAn+1
-
the enzyme has a key role in V(D)J recombination during lymphocyte and repertoire development
-
-
?
deoxynucleoside triphosphate + DNAn
diphosphate + DNAn+1
-
-
-
-
?
deoxynucleoside triphosphate + DNAn
diphosphate + DNAn+1
-
primer required
-
?
deoxynucleoside triphosphate + DNAn
diphosphate + DNAn+1
-
primer required
-
?
deoxynucleoside triphosphate + DNAn
diphosphate + DNAn+1
-
primer required
-
?
deoxynucleoside triphosphate + DNAn
diphosphate + DNAn+1
-
primer required
-
?
deoxynucleoside triphosphate + DNAn
diphosphate + DNAn+1
-
primer required
-
?
deoxynucleoside triphosphate + DNAn
diphosphate + DNAn+1
-
primer required
-
?
deoxynucleoside triphosphate + DNAn
diphosphate + DNAn+1
-
primer required
-
?
deoxynucleoside triphosphate + DNAn
diphosphate + DNAn+1
-
primer required
-
?
deoxynucleoside triphosphate + DNAn
diphosphate + DNAn+1
-
primer required
-
?
deoxynucleoside triphosphate + DNAn
diphosphate + DNAn+1
-
primer required
-
?
deoxynucleoside triphosphate + DNAn
diphosphate + DNAn+1
-
primer required
-
?
deoxynucleoside triphosphate + DNAn
diphosphate + DNAn+1
-
primer required
-
?
deoxynucleoside triphosphate + DNAn
diphosphate + DNAn+1
-
primer required
-
?
deoxynucleoside triphosphate + DNAn
diphosphate + DNAn+1
-
primer required
-
?
deoxynucleoside triphosphate + DNAn
diphosphate + DNAn+1
-
primer required
-
?
deoxynucleoside triphosphate + DNAn
diphosphate + DNAn+1
-
primer required
-
?
deoxynucleoside triphosphate + DNAn
diphosphate + DNAn+1
-
primer required
-
?
deoxynucleoside triphosphate + DNAn
diphosphate + DNAn+1
-
primer required
-
ir
deoxynucleoside triphosphate + DNAn
diphosphate + DNAn+1
-
primer required
-
ir
deoxynucleoside triphosphate + DNAn
diphosphate + DNAn+1
-
primer required
-
ir
deoxynucleoside triphosphate + DNAn
diphosphate + DNAn+1
-
primer: DNase II-treated DNA
-
ir
deoxynucleoside triphosphate + DNAn
diphosphate + DNAn+1
-
longer chains interact well with the enzyme, but synthesis rate decreases
-
ir
deoxynucleoside triphosphate + DNAn
diphosphate + DNAn+1
-
primer: oligonucleotides containing at least 3 phosphate groups and a free 3'-hydroxyl end
-
ir
deoxynucleoside triphosphate + DNAn
diphosphate + DNAn+1
-
no nucleotide specificity
-
ir
deoxynucleoside triphosphate + DNAn
diphosphate + DNAn+1
-
primer: DNase I-treated DNA
-
ir
deoxynucleoside triphosphate + DNAn
diphosphate + DNAn+1
-
enzyme also catalyzes diphosphate exchange and pyrophosphorolysis
-
?
deoxynucleoside triphosphate + DNAn
diphosphate + DNAn+1
-
reaction is not template directed
-
?
deoxynucleoside triphosphate + DNAn
diphosphate + DNAn+1
-
reaction is not template directed
-
?
deoxynucleoside triphosphate + DNAn
diphosphate + DNAn+1
-
reaction is not template directed
-
?
deoxynucleoside triphosphate + DNAn
diphosphate + DNAn+1
-
reaction is not template directed
-
?
deoxynucleoside triphosphate + DNAn
diphosphate + DNAn+1
-
reaction is not template directed
-
?
deoxynucleoside triphosphate + DNAn
diphosphate + DNAn+1
-
reaction is not template directed
-
?
deoxynucleoside triphosphate + DNAn
diphosphate + DNAn+1
-
reaction is not template directed
-
?
deoxynucleoside triphosphate + DNAn
diphosphate + DNAn+1
-
reaction is not template directed
-
?
deoxynucleoside triphosphate + DNAn
diphosphate + DNAn+1
-
reaction is not template directed
-
?
deoxynucleoside triphosphate + DNAn
diphosphate + DNAn+1
-
reaction is not template directed
-
?
deoxynucleoside triphosphate + DNAn
diphosphate + DNAn+1
-
reaction is not template directed
-
?
deoxynucleoside triphosphate + DNAn
diphosphate + DNAn+1
-
reaction is not template directed
-
?
deoxynucleoside triphosphate + DNAn
diphosphate + DNAn+1
-
reaction is not template directed
-
?
deoxynucleoside triphosphate + DNAn
diphosphate + DNAn+1
-
reaction is not template directed
-
?
deoxynucleoside triphosphate + DNAn
diphosphate + DNAn+1
-
reaction is not template directed
-
?
deoxynucleoside triphosphate + DNAn
diphosphate + DNAn+1
-
reaction is not template directed
-
?
deoxynucleoside triphosphate + DNAn
diphosphate + DNAn+1
-
reaction is not template directed
-
?
deoxynucleoside triphosphate + DNAn
diphosphate + DNAn+1
-
reaction is not template directed
-
ir
deoxynucleoside triphosphate + DNAn
diphosphate + DNAn+1
-
reaction is not template directed
-
ir
deoxynucleoside triphosphate + DNAn
diphosphate + DNAn+1
-
reaction is not template directed
-
ir
deoxynucleoside triphosphate + DNAn
diphosphate + DNAn+1
-
as the initiator chain length is increased to 5-7 nucleotides the polymerization rate also increases
-
ir
deoxynucleoside triphosphate + DNAn
diphosphate + DNAn+1
-
primer: heat-denatured DNA
-
ir
deoxynucleoside triphosphate + DNAn
diphosphate + DNAn+1
-
phosphorthioate primers with internucleotide linkages in [RP] configuration are used efficiently, while linkages in [SP] configuration decrease significantly primer extension reaction
-
-
?
deoxynucleoside triphosphate + DNAn
diphosphate + DNAn+1
-
relative rates of polymerization with several nucleotides
-
ir
additional information
?
-
wild type enzyme is unable to incorporate bulky 3'-blocked nucleotides due to steric clashes
-
-
-
additional information
?
-
-
enzyme additionally has oligodeoxynucleotidyl kinase activity, substrates are triphosphates modified at Palpha,beta,gamma-residues
-
-
?
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(E)-5-(2-bromovinyl)-2'-deoxyuridine 5'-triphosphate
-
-
1,10-phenanthroline
-
not m-isomer
2',3'-dideoxyadenosine
-
inhibition is stronger with (dA)12-18 as primer than with heat denatured DNA, substrate ATP, 50% inhibition at 0.006 mM
2',3'-dideoxycytidine
-
inhibition is stronger with (dA)12-18 as primer than with heat denatured DNA, substrate CTP, 50% inhibition at 0.002 mM
2',3'-dideoxyguanosine
-
inhibition is stronger with (dA)12-18 as primer than with heat denatured DNA, substrate GTP, 50% inhibition at 0.005 mM
2',3'-dideoxythymidine
-
inhibition is stronger with (dA)12-18 as primer than with heat denatured DNA, substrate TTP, 50% inhibition at 0.020 mM
2',3'-dideoxythymidine 5'-triphosphate
-
-
3'-dATP
-
selective inhibitor, inactive in DNA-synthesizing systems both with DNA polymerase alpha or beta
3'-Deoxy-3'-fluorothymidine 5'-triphosphate
-
-
5-(hydroxymethyl)-2-furfural
-
HMF, a pyrolysate of carbohydrate isolated from instant coffee (CoVea arabica L.)
6-(1-phenyl-1H-indol-3-yl)-2,4-dioxy-5-hexenoic acid
-
IC50: 0.0472 mM
6-(1-phenylmethyl-1H-indol-3-yl)-2,4-dioxy-5-hexenoic acid
-
IC50: 0.0079 mM
6-(4-benzoyl-1-phenylmethyl-1H-pyrrol-2-yl)-2,4-dioxo-5-hexenoic acid
-
IC50: 0.0162 mM
9-alpha-Arabinofuranosyladenine 5'-triphosphate
-
-
9-beta-arabinofuranosyladenine 5'-triphosphate
-
-
ATP
-
selective inhibitor, inactive in DNA-synthesizing systems both with DNA polymerase alpha or beta
dATP
-
mechanism of Mn2+-dependent inhibition
diadenosine 5',5'-diphosphate
-
-
diadenosine 5',5'-hexaphosphate
-
-
diadenosine 5',5'-pentaphosphate
-
-
diadenosine 5',5'-tetraphosphate
diadenosine 5',5'-triphosphate
-
-
high ionic strength
-
-
-
L-beta-deoxythymidine-triphosphate
-
i.e. L-dTTP, competitive
additional information
-
Allium sativa extract is a mixture of diallyl trisulfide, diallyl tetrasulfide, and diallyl pentasulfide exhibiting an IC50 value of 0.371 mM at 37°C and a KI value of 0.0121 mM at 37°C
-
diadenosine 5',5'-tetraphosphate
-
-
diadenosine 5',5'-tetraphosphate
-
i.e. AP4A, strong
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Krakow, J.S.; Coutsogeorgopoulos, C.; Canellakis, E.S.
Studies on the incorporation of deoxyribonucleotides and ribonucleotides into deoxyribonucleic acid
Biochim. Biophys. Acta
55
639-650
1962
Bos taurus
brenda
Gottesman, M.E.; Canellakis, E.S.
The terminal nucleotidyltransferases of calf thymus nuclei
J. Biol. Chem.
241
4339-4352
1966
Bos taurus
brenda
Chang, L.M.S.; Bollum, F.J.
Deoxynucleotide-polymerizing enzymes of calf thymus gland. V. Homogeneous terminal deoxynucleotidyl transferase
J. Biol. Chem.
246
909-916
1971
Bos taurus
brenda
Pandey, V.; Modak, M.J.
Purification of high molecular mass species of calf thymus terminal deoxynucleotidyltransferase
Prep. Biochem.
17
359-377
1987
Bos taurus
brenda
Matthes, E.; Lehman, C.; Drescher, B.; Buettner, W.; Langen, P.
3-Deoxy-3-fluorothymidinetriphosphate: inhibitor and terminator of DNA synthesis catalysed by DNA polymerase beta, terminal deoxynucleotidyl transferase and DNA polymerase I
Biomed. Biochim. Acta
44
K63-K73
1985
Bos taurus
brenda
Deibel, M.R.; Coleman, M.S.; Acree, K.; Hutton, J.J.
Biochemical and immunological properties of human terminal deoxynucleotidyl transferase purified from blasts of acute lymphoblastic and chronic myelogenous leukemia
J. Clin. Invest.
67
725-734
1981
Bos taurus, Homo sapiens
brenda
Ratliff, R.L.
Terminal deoxyribonucleotidyl transferase
The Enzymes,3rd Ed. (Boyer,P. D. ,ed. )
14
105-118
1981
Bos taurus, Homo sapiens, Mus musculus
-
brenda
Bollum, F.J.
Terminal deoxyribonucleotidyl transferase
The Enzymes,3rd Ed. (Boyer,P. D. ,ed. )
10
145-171
1974
Bos taurus
-
brenda
Bollum, F.J.
Terminal deoxynucleotidyl transferase: biological studies
Adv. Enzymol. Relat. Areas Mol. Biol.
47
347-374
1978
Bos taurus
brenda
Mller, W.E.G.; Zahn, R.K.; Arendes, J.
Differential mode of inhibition of terminal deoxynucleotidyl transferase by 3-dATP, ATP, betaaraATP and alphaaraATP
FEBS Lett.
94
47-50
1978
Bos taurus
brenda
Coleman, M.S.
Terminal deoxynucleotidyl transferase: characterization of extraction and assay conditions from human and calf tissue
Arch. Biochem. Biophys.
182
525-532
1977
Bos taurus, Homo sapiens
brenda
Ono, K.; Nakane, H.; Colla, L.; De Clercq, E.
Inhibition of terminal deoxyribonucleotidyltransferase by (E)-5-(2-bromovinyl)-2-deoxyuridine 5-triphosphate
Nucleic Acids Res.
12
123-126
1983
Bos taurus
-
brenda
Ono, K.; Iwata, Y.; Nakamura, H.; Matsukage, A.
Selective inhibition of terminal deoxynucleotidyl transferase by diadenosine 5,5-P1,P4-tetraphosphate
Biochem. Biophys. Res. Commun.
95
34-40
1980
Bos taurus
brenda
Fuller, S.A.; Philips, A.; Coleman, M.S.
Affinity purification and refined structural characterization of terminal deoxynucleotidyltransferase
Biochem. J.
231
105-113
1985
Bos taurus
brenda
Ono, K.
Inhibitory effects of various 2,3-dideoxynucleoside 5-triphosphates on the utilization of 2-deoxynucleoside 5-triphosphates by terminal deoxynucleotidyltransferase from calf thymus
Biochim. Biophys. Acta
1049
15-20
1990
Bos taurus
brenda
Pandey, V.N.; Amrute, S.B.; Satav, J.G.; Modak, M.J.
Inhibition of terminal deoxynucleotidyl trasnferase by adenine dinucleotides
FEBS Lett.
213
205-208
1987
Bos taurus
-
brenda
Srivastava, A.; Modak, M.J.
Biochemistry of terminal deoxynucleotidyltransferase: identification, characterization, requirements, and active-site involvement in the catalysis of associated pyrophosphate exchange and pyrophosphorolytic activity
Biochemistry
19
3270-3275
1980
Bos taurus
brenda
Modak, M.J.
Biochemistry of terminal deoxynucleotidyltransferase. Mechanism of manganese-dependent inhibition by deoxyadenosine 5-triphosphate and biological implications
Biochemistry
18
2679-2684
1979
Bos taurus
brenda
Nakamura, H.; Tanabe, K.; Yoshida, S.; Morita, T.
Terminal deoxynucleotidyltransferase of 60,000 daltons from mouse, rat, and calf thymus. Purification by immunoadsorbent chromatography and comparison of peptide structures
J. Biol. Chem.
256
8745-8751
1981
Bos taurus, Mus musculus, Rattus norvegicus
brenda
Okamura, S.; Crane, F.; Messner, H.A.; Mak, T.W.
Purification of terminal deoxynucleotidyltransferase by oligonucleotide affinity chromatography
J. Biol. Chem.
253
3765-3767
1978
Bos taurus, Homo sapiens
brenda
Yamadori, I.; Yoshino, T.; Kondo, E.; Cao, L.; Akagi, T.; Matsuo, Y.; Minowada, J.
Comparison of two methods of staining apoptotic cells of leukemia cell lines: terminal deoxynucleotidyl transferase and DNA polymerase I reactions
J. Histochem. Cytochem.
46
85-90
1998
Bos taurus
brenda
Focher, F.; Maga, G.; Bendiscioli, A.; Capobianco, M.; Colonna, F.; Garbesi, A.; Spadari, S.
Stereospecificity of human DNA polymerases alpha, beta, gamma, delta and epsilon, HIV-reverse transcriptase, HSV-1 DNA polymerase, calf thymus terminal transferase and Escherichia coli DNA polymerase I in recognizing D- and L-thymidine 5'-triphosphate as substrate
Nucleic Acids Res.
23
2840-2847
1995
Bos taurus
brenda
Koziolkiewicz, M.; Maciaszek, A.; Stec, W.J.; Semizarov, D.; Victorova, L.; Krayevsky, A.
Effect of P-chirality of oligo(deoxyribonucleoside phosphorothioate)s on the activity of terminal deoxyribonucleotidyl transferase
FEBS Lett.
434
77-82
1998
Bos taurus
brenda
Arzumanov, A.A.; Victorova, L.S.; Jasko, M.V.; Yesipov, D.S.; Krayevsky, A.A.
Terminal deoxynucleotidyl transferase catalyzes the reaction of DNA phosphorylation
Nucleic Acids Res.
28
1276-1281
2000
Bos taurus
brenda
Thai, T.H.; Kearney, J.F.
Isoforms of terminal deoxynucleotidyltransferase: Developmental aspects and function
Adv. Immunol.
86
113-136
2005
Bos taurus, Homo sapiens, Mus musculus, Rattus norvegicus
brenda
Locatelli, G.A.; Di Santo, R.; Crespan, E.; Costi, R.; Roux, A.; Hubscher, U.; Shevelev, I.; Blanca, G.; Villani, G.; Spadari, S.; Maga, G.
Diketo hexenoic acid derivatives are novel selective non-nucleoside inhibitors of mammalian terminal deoxynucleotidyl transferases, with potent cytotoxic effect against leukemic cells
Mol. Pharmacol.
68
538-550
2005
Bos taurus
brenda
Mizushina, Y.; Yagita, E.; Kuramochi, K.; Kuriyama, I.; Shimazaki, N.; Koiwai, O.; Uchiyama, Y.; Yomezawa, Y.; Sugawara, F.; Kobayashi, S.; Sakaguchi, K.; Yoshida, H.
5-(Hydroxymethyl)-2-furfural: a selective inhibitor of DNA polymerase lambda and terminal deoxynucleotidyltransferase
Arch. Biochem. Biophys.
446
69-76
2006
Bos taurus
brenda
Fowler, J.D.; Suo, Z.
Biochemical, structural, and physiological characterization of terminal deoxynucleotidyl transferase
Chem. Rev.
106
2092-2110
2006
Bos taurus, Mus musculus
brenda
Cho, Y.; Kool, E.T.
Enzymatic synthesis of fluorescent oligomers assembled on a DNA backbone
ChemBioChem
7
669-672
2006
Bos taurus
brenda
Anne, A.; Bonnaudat, C.; Demaille, C.; Wang, K.
Enzymatic redox 3-end-labeling of DNA oligonucleotide monolayers on gold surfaces using terminal deoxynucleotidyl transferase (TdT)-mediated single base extension
J. Am. Chem. Soc.
129
2734-2735
2007
Bos taurus
brenda
Nishida, M.; Hada, T.; Kuramochi, K.; Yoshida, H.; Yonezawa, Y.; Kuriyama, I.; Sugawara, F.; Yoshida, H.; Mizushina, Y.
Diallyl sulfides: Selective inhibitors of family X DNA polymerases from garlic (Allium sativum L.)
Food Chem.
108
551-560
2008
Bos taurus
brenda
Zhao, B.; Gong, Z.; Ma, Z.; Wang, D.; Jin, Y.
Simple and sensitive microRNA labeling by terminal deoxynucleotidyl transferase
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Bos taurus
brenda
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Tail-labelling of DNA probes using modified deoxynucleotide triphosphates and terminal deoxynucleotidyl transferase. Application in electrochemical DNA hybridization and protein-DNA binding assays
Org. Biomol. Chem.
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Bos taurus (P06526)
brenda
Maezawa, S.; Fukushima, R.; Matsushita, T.; Kato, T.; Takagaki, Y.; Nishiyama, Y.; Ando, S.; Matsumoto, T.; Kouda, K.; Hayano, T.; Suzuki, M.; Koiwai, K.; Koiwai, O.
Ubiquitylation of terminal deoxynucleotidyltransferase inhibits its activity
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Bos taurus
brenda
Chua, J.P.S.; Go, M.K.; Osothprarop, T.; Mcdonald, S.; Karabadzhak, A.G.; Yew, W.S.; Peisajovich, S.; Nirantar, S.
Evolving a thermostable terminal deoxynucleotidyl transferase
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Bos taurus (P06526)
brenda
Tauraite, D.; Jakubovska, J.; Dabuzinskaite, J.; Bratchikov, M.; Meskys, R.
Modified nucleotides as substrates of terminal deoxynucleotidyl transferase
Molecules
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Bos taurus (P06526)
brenda
Wang, Y.; Liu, J.; Zhou, H.
Visual detection of cucumber green mottle mosaic virus based on terminal deoxynucleotidyl transferase coupled with DNAzymes amplification
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Bos taurus (P06526)
brenda