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Literature summary for 2.7.7.31 extracted from

  • Nishida, M.; Hada, T.; Kuramochi, K.; Yoshida, H.; Yonezawa, Y.; Kuriyama, I.; Sugawara, F.; Yoshida, H.; Mizushina, Y.
    Diallyl sulfides: Selective inhibitors of family X DNA polymerases from garlic (Allium sativum L.) (2008), Food Chem., 108, 551-560.
    View publication on PubMed
Search for more literature for 2.7.7.31

Inhibitors

Inhibitors Comment Organism Structure
diallyl trisulfide
-
 Bos taurus
additional information Allium sativa extract is a mixture of diallyl trisulfide, diallyl tetrasulfide, and diallyl pentasulfide exhibiting an IC50 value of 0.371 mM at 37°C and a KI value of 0.0121 mM at 37°C Bos taurus

KM Value [mM]

KM Value [mM] KM Value Maximum [mM] Substrate Comment Organism Structure
1.02
-
 dTTP at 37°C Bos taurus

Organism

Organism UniProt Comment Textmining
Bos taurus
-
-
-

Substrates and Products (Substrate)

Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
deoxynucleoside triphosphate + DNAn
-
 Bos taurus diphosphate + DNAn+1
-
 ?
dTTP + DNAn
-
 Bos taurus ?
-
 ?

Synonyms

Synonyms Comment Organism
TdT
-
 Bos taurus
terminal deoxynucleotidyl transferase
-
 Bos taurus

IC50 Value

IC50 Value IC50 Value Maximum Comment Organism Inhibitor Structure
0.144
-
 at 37°C Bos taurus diallyl trisulfide