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Information on EC 2.6.1.88 - methionine transaminase

for references in articles please use BRENDA:EC2.6.1.88

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IUBMB Comments

The enzyme is most active with L-methionine. It participates in the L-methionine salvage pathway from S-methyl-5′-thioadenosine, a by-product of polyamine biosynthesis. The enzyme from the bacterium Klebsiella pneumoniae can use several different amino acids as amino donor, with aromatic amino acids being the most effective . The enzyme from the plant Arabidopsis thaliana is also a part of the chain elongation pathway in the biosynthesis of methionine-derived glucosinolates .

The expected taxonomic range for this enzyme is: Bacteria, Eukaryota, Archaea

Synonyms
methionine aminotransferase, methionine transaminase, more

REACTION
REACTION DIAGRAM
COMMENTARY hide
ORGANISM
UNIPROT
LITERATURE
L-methionine + a 2-oxo carboxylate = 4-(methylsulfanyl)-2-oxobutanoate + an L-amino acid
show the reaction diagram
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PATHWAY SOURCE
PATHWAYS
MetaCyc
dimethylsulfoniopropanoate biosynthesis III (algae and phytoplankton), ethene biosynthesis III (microbes), L-homomethionine biosynthesis
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