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Information on EC 2.5.1.136 - 2-acylphloroglucinol 4-prenyltransferase

for references in articles please use BRENDA:EC2.5.1.136
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IUBMB Comments
The enzyme, characterized from hop (Humulus lupulus), acts on phlorisovalerophenone, phlormethylbutanophenone, and phlorisobutanophenone during the synthesis of bitter acids. It also acts with much lower activity on naringenin chalcone. Forms a complex with EC 2.5.1.137, 2-acyl-4-prenylphloroglucinol 6-prenyltransferase, which catalyses additional prenylation reactions. Requires Mg2+.
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The expected taxonomic range for this enzyme is: Humulus lupulus
Synonyms
aromatic prenyltransferase, PT-1, PT1, PT1L, more
REACTION
REACTION DIAGRAM
COMMENTARY hide
ORGANISM
UNIPROT
LITERATURE
dimethylallyl diphosphate + a 2-acylphloroglucinol = diphosphate + a 2-acyl-4-prenylphloroglucinol
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