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Synonyms
o-linked n-acetylglucosamine transferase, ogt protein, o-glcnac protein, n-acetylglucosamine transferase, o-glcnac-transferase, human ogt, ncogt, secret agent, o-linked glcnac transferase, o-linked n-acetylglucosaminyltransferase,
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capsid protein of Plum pox virus + UDP-N-acetyl-D-glucosamine
UDP + N-acetyl-D-glucosaminyl-[capsid protein of Plum pox virus]
capsid protein of Plum pox virus + UDP-N-acetyl-D-glucosamine
UDP + N-acetyl-D-glucosaminyl-[capsid protein of Plum pox virus]
additional information
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capsid protein of Plum pox virus + UDP-N-acetyl-D-glucosamine
UDP + N-acetyl-D-glucosaminyl-[capsid protein of Plum pox virus]
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capsid protein of Plum pox virus + UDP-N-acetyl-D-glucosamine
UDP + N-acetyl-D-glucosaminyl-[capsid protein of Plum pox virus]
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capsid protein of Plum pox virus + UDP-N-acetyl-D-glucosamine
UDP + N-acetyl-D-glucosaminyl-[capsid protein of Plum pox virus]
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capsid protein of Plum pox virus + UDP-N-acetyl-D-glucosamine
UDP + N-acetyl-D-glucosaminyl-[capsid protein of Plum pox virus]
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additional information
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catalyzes the transfer of N-acetylglucosamine (GlcNAc) from UDP-GlcNAc to Ser/Thr residues of proteins
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additional information
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catalyzes the transfer of N-acetylglucosamine (GlcNAc) from UDP-GlcNAc to Ser/Thr residues of proteins
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additional information
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enzyme modifies the Plum pox virus capsid protein
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additional information
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enzyme modifies the Plum pox virus capsid protein
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additional information
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enzyme modifies the Plum pox virus capsid protein
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additional information
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participates in plum pox virus infection, plants are inoculated with PPV-NK-GFP and observed at different times postinoculation under a fluorescence microscope
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additional information
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participates in plum pox virus infection, plants are inoculated with PPV-NK-GFP and observed at different times postinoculation under a fluorescence microscope
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?
additional information
?
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participates in plum pox virus infection, plants are inoculated with PPV-NK-GFP and observed at different times postinoculation under a fluorescence microscope
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?
additional information
?
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enzyme adds a single GlcNAc to hydroxyl groups of serine and threonine residues. In the plant Arabidopsis, OGT serves to attenuate the gibberillin pathway
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additional information
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enzyme modifies the Plum pox virus capsid protein
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?
additional information
?
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enzyme modifies the Plum pox virus capsid protein
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?
additional information
?
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enzyme modifies the Plum pox virus capsid protein
-
-
?
additional information
?
-
participates in plum pox virus infection, plants are inoculated with PPV-NK-GFP and observed at different times postinoculation under a fluorescence microscope
-
-
?
additional information
?
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participates in plum pox virus infection, plants are inoculated with PPV-NK-GFP and observed at different times postinoculation under a fluorescence microscope
-
-
?
additional information
?
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-
participates in plum pox virus infection, plants are inoculated with PPV-NK-GFP and observed at different times postinoculation under a fluorescence microscope
-
-
?
Please wait a moment until the data is sorted. This message will disappear when the data is sorted.
additional information
?
-
additional information
?
-
catalyzes the transfer of N-acetylglucosamine (GlcNAc) from UDP-GlcNAc to Ser/Thr residues of proteins
-
-
?
additional information
?
-
-
catalyzes the transfer of N-acetylglucosamine (GlcNAc) from UDP-GlcNAc to Ser/Thr residues of proteins
-
-
?
additional information
?
-
enzyme modifies the Plum pox virus capsid protein
-
-
?
additional information
?
-
enzyme modifies the Plum pox virus capsid protein
-
-
?
additional information
?
-
-
enzyme modifies the Plum pox virus capsid protein
-
-
?
additional information
?
-
participates in plum pox virus infection, plants are inoculated with PPV-NK-GFP and observed at different times postinoculation under a fluorescence microscope
-
-
?
additional information
?
-
participates in plum pox virus infection, plants are inoculated with PPV-NK-GFP and observed at different times postinoculation under a fluorescence microscope
-
-
?
additional information
?
-
-
participates in plum pox virus infection, plants are inoculated with PPV-NK-GFP and observed at different times postinoculation under a fluorescence microscope
-
-
?
additional information
?
-
-
enzyme adds a single GlcNAc to hydroxyl groups of serine and threonine residues. In the plant Arabidopsis, OGT serves to attenuate the gibberillin pathway
-
-
?
additional information
?
-
enzyme modifies the Plum pox virus capsid protein
-
-
?
additional information
?
-
enzyme modifies the Plum pox virus capsid protein
-
-
?
additional information
?
-
-
enzyme modifies the Plum pox virus capsid protein
-
-
?
additional information
?
-
participates in plum pox virus infection, plants are inoculated with PPV-NK-GFP and observed at different times postinoculation under a fluorescence microscope
-
-
?
additional information
?
-
participates in plum pox virus infection, plants are inoculated with PPV-NK-GFP and observed at different times postinoculation under a fluorescence microscope
-
-
?
additional information
?
-
-
participates in plum pox virus infection, plants are inoculated with PPV-NK-GFP and observed at different times postinoculation under a fluorescence microscope
-
-
?
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sec spy double mutant
double-mutant embryos aborted at various stages of development and no double-mutant seedlings are obtained. These results indicate that OGT activity is required during gametogenesis and embryogenesis with lethality occurring when parentally derived SEC, SPY, and/or O-GlcNAcylated proteins become limiting
sec-1
has a tDNA insertion within the exon encoding the ninth tetratricopeptide repeat, no obvious phenotype. Two SEC tDNA insertional mutants are identified and analyzed. sec mutant plants do not exhibit obvious phenotypes, sec and spy mutations have a synthetic lethal interaction
sec-2
contains an insertion within an intron adjacent to exons encoding the putative catalytic portion of the protein, no obvious phenotype. Two SEC tDNA insertional mutants are identified and analyzed. sec mutant plants do not exhibit obvious phenotypes, sec and spy mutations have a synthetic lethal interaction
spy-3
Columbia (Col-0) background, has a Gly-to-Ser substitution in the C-terminal region of the protein. The spy plants have defects in a number of processes, including gibberellin and cytokinin responses, flowering, circadian regulation, and light inhibition of hypocotyls elongation
additional information
deletion mapping and site-directed mutagenesis identified three threonine and a serine located near the N-terminus of PPV-CP that are modified by SEC
additional information
deletion mapping and site-directed mutagenesis identified three threonine and a serine located near the N-terminus of PPV-CP that are modified by SEC
additional information
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deletion mapping and site-directed mutagenesis identified three threonine and a serine located near the N-terminus of PPV-CP that are modified by SEC
additional information
plum pox virus is able to infect the Arabidopsis OGT mutants sec-1, sec-2, and spy-3, but at early times of the infection, both rate of virus spread and accumulation are reduced in sec-1 and sec-2 relative to spy-3 and wild-type plants
additional information
plum pox virus is able to infect the Arabidopsis OGT mutants sec-1, sec-2, and spy-3, but at early times of the infection, both rate of virus spread and accumulation are reduced in sec-1 and sec-2 relative to spy-3 and wild-type plants
additional information
-
plum pox virus is able to infect the Arabidopsis OGT mutants sec-1, sec-2, and spy-3, but at early times of the infection, both rate of virus spread and accumulation are reduced in sec-1 and sec-2 relative to spy-3 and wild-type plants
additional information
sec-1, Wassilewskija background, T-DNA is inserted into the tetratricopeptide repeat domain, no obvious phenotype
additional information
sec-1, Wassilewskija background, T-DNA is inserted into the tetratricopeptide repeat domain, no obvious phenotype
additional information
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sec-1, Wassilewskija background, T-DNA is inserted into the tetratricopeptide repeat domain, no obvious phenotype
additional information
sec-2, Columbia (Col-0) background. T-DNA is inserted into an intron adjacent to exons coding for the putative catalytic region of the protein, no obvious phenotype
additional information
sec-2, Columbia (Col-0) background. T-DNA is inserted into an intron adjacent to exons coding for the putative catalytic region of the protein, no obvious phenotype
additional information
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sec-2, Columbia (Col-0) background. T-DNA is inserted into an intron adjacent to exons coding for the putative catalytic region of the protein, no obvious phenotype
additional information
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deletional or disrupting mutation of the Spindly SPY locus affects the enzyme and the plant signaling, e.g. increased gibberillin signaling, altered phenotypes
additional information
plum pox virus is able to infect the Arabidopsis OGT mutants sec-1, sec-2, and spy-3, but at early times of the infection, both rate of virus spread and accumulation are reduced in sec-1 and sec-2 relative to spy-3 and wild-type plants
additional information
plum pox virus is able to infect the Arabidopsis OGT mutants sec-1, sec-2, and spy-3, but at early times of the infection, both rate of virus spread and accumulation are reduced in sec-1 and sec-2 relative to spy-3 and wild-type plants
additional information
-
plum pox virus is able to infect the Arabidopsis OGT mutants sec-1, sec-2, and spy-3, but at early times of the infection, both rate of virus spread and accumulation are reduced in sec-1 and sec-2 relative to spy-3 and wild-type plants
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Roos, M.D.; Hanover, J.A.
Structure of O-linked GlcNAc transferase: Mediator of glycan-dependent signaling
Biochem. Biophys. Res. Commun.
271
275-280
2000
Arabidopsis thaliana, Homo sapiens, no activity in Saccharomyces cerevisiae, no activity in Escherichia coli, Rhodobacter sp.
brenda
Chen, D.; Juarez, S.; Hartweck, L.; Alamillo, J.M.; Simon-Mateo, C.; Perez, J.J.; Fernandez-Fernandez, M.R.; Olszewski, N.E.; Garcia, J.A.
Identification of secret agent as the O-GlcNAc transferase that participates in Plum pox virus infection
J. Virol.
79
9381-9387
2005
Arabidopsis thaliana (Q96301), Arabidopsis thaliana (Q9M8Y0), Arabidopsis thaliana, Nicotiana benthamiana
brenda
Scott, C.L.; Hartweck, L.M.; de Jesus Perez, J.; Chen, D.; Garcia, J.A.; Olszewski, N.E.
SECRET AGENT, an Arabidopsis thaliana O-GlcNAc transferase, modifies the Plum pox virus capsid protein
FEBS Lett.
580
5829-5835
2006
Arabidopsis thaliana (Q96301), Arabidopsis thaliana (Q9M8Y0), Arabidopsis thaliana
brenda
Hartweck, L.M.; Scott, C.L.; Olszewski, N.E.
Two O-linked N-acetylglucosamine transferase genes of Arabidopsis thaliana L. Heynh. have overlapping functions necessary for gamete and seed development
Genetics
161
1279-1291
2002
Arabidopsis thaliana (Q9M8Y0), Arabidopsis thaliana
brenda
Xing, L.; Liu, Y.; Xu, S.; Xiao, J.; Wang, B.; Deng, H.; Lu, Z.; Xu, Y.; Chong, K.
Arabidopsis O-GlcNAc transferase SEC activates histone methyltransferase ATX1 to regulate flowering
EMBO J.
37
e98115
2018
Arabidopsis thaliana (Q9M8Y0)
brenda