Reference on EC 2.3.1.50 - serine C-palmitoyltransferase and Organism(s) Mus musculus and UniProt Accession P97363
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AUTHORS
TITLE
JOURNAL
VOL.
PAGES
YEAR
ORGANISM (UNIPROT)
PUBMED ID
SOURCE
Weiss, B.; Stoffel, W.
Human and murine serine-palmitoyl-CoA transferase. Cloning, expression and characterization of the key enzyme in sphingolipid synthesis
Eur. J. Biochem.
249
239-247
1997
Homo sapiens, Mus musculus
Van Echten-Deckert, G.; Zschoche, A.; Bar, T.; Schmidt, R.R.; Raths, A.; Heinemann, T.; Sandhoff, K.
cis-4-Methylsphingosine decreases sphingolipid biosynthesis by specifically interfering with serine palmitoyltransferase activity in primary cultured neurons
J. Biol. Chem.
272
15825-15833
1997
Mus musculus
Perry, D.K.
Serine palmitoyltransferase: role in apoptotic de novo ceramide synthesis and other stress responses
Biochim. Biophys. Acta
1585
146-152
2002
Saccharomyces cerevisiae, Homo sapiens, Mus musculus
Lightle, S.; Tosheva, R.; Lee, A.; Queen-Baker, J.; Boyanovsky, B.; Shedlofsky, S.; Nikolova-Karakashian, M.
Elevation of ceramide in serum lipoproteins during acute phase response in humans and mice: role of serine-palmitoyl transferase
Arch. Biochem. Biophys.
419
120-128
2003
Homo sapiens, Mus musculus
Dobrzyn, A.; Dobrzyn, P.; Lee, S.; Miyazaki, M.; Cohen, P.; Asilmaz, E.; Hardie, D.G.; Friedman, J.M.; Ntambi, J.M.
Stearoyl-CoA desaturase-1 deficiency reduces ceramide synthesis by downregulating serine palmitoyltransferase and increasing beta-oxidation in skeletal muscle
Am. J. Physiol.
288
E599-E607
2005
Mus musculus
Glaros, E.N.; Kim, W.S.; Wu, B.J.; Suarna, C.; Quinn, C.M.; Rye, K.A.; Stocker, R.; Jessup, W.; Garner, B.
Inhibition of atherosclerosis by the serine palmitoyl transferase inhibitor myriocin is associated with reduced plasma glycosphingolipid concentration
Biochem. Pharmacol.
73
1340-1346
2007
Mus musculus
Park, T.S.; Rosebury, W.; Kindt, E.K.; Kowala, M.C.; Panek, R.L.
Serine palmitoyltransferase inhibitor myriocin induces the regression of atherosclerotic plaques in hyperlipidemic ApoE-deficient mice
Pharmacol. Res.
58
45-51
2008
Mus musculus
