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Information on EC 1.8.4.10 - adenylyl-sulfate reductase (thioredoxin) and Organism(s) Burkholderia cepacia and UniProt Accession Q9RFS6

for references in articles please use BRENDA:EC1.8.4.10
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EC Tree
IUBMB Comments
Uses adenylyl sulfate, not phosphoadenylyl sulfate, distinguishing this enzyme from EC 1.8.4.8, phosphoadenylyl-sulfate reductase (thioredoxin). Uses thioredoxin as electron donor, not glutathione or other donors, distinguishing it from EC 1.8.4.9 [adenylyl-sulfate reductase (glutathione)] and EC 1.8.99.2 (adenylyl-sulfate reductase).
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This record set is specific for:
Burkholderia cepacia
UNIPROT: Q9RFS6
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Word Map
The taxonomic range for the selected organisms is: Burkholderia cepacia
The expected taxonomic range for this enzyme is: Bacteria, Eukaryota, Archaea
Synonyms
paapr, apr-b, thioredoxin-dependent aps reductase, more
SYNONYM
ORGANISM
UNIPROT
COMMENTARY hide
LITERATURE
thioredoxin dependent 5'-adenylylsulfate reductase
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REACTION TYPE
ORGANISM
UNIPROT
COMMENTARY hide
LITERATURE
redox reaction
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oxidation
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reduction
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PATHWAY SOURCE
PATHWAYS
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SYSTEMATIC NAME
IUBMB Comments
AMP,sulfite:thioredoxin-disulfide oxidoreductase (adenosine-5'-phosphosulfate-forming)
Uses adenylyl sulfate, not phosphoadenylyl sulfate, distinguishing this enzyme from EC 1.8.4.8, phosphoadenylyl-sulfate reductase (thioredoxin). Uses thioredoxin as electron donor, not glutathione or other donors, distinguishing it from EC 1.8.4.9 [adenylyl-sulfate reductase (glutathione)] and EC 1.8.99.2 (adenylyl-sulfate reductase).
CAS REGISTRY NUMBER
COMMENTARY hide
9027-75-2
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SUBSTRATE
PRODUCT                       
REACTION DIAGRAM
ORGANISM
UNIPROT
COMMENTARY
(Substrate) hide
LITERATURE
(Substrate)
COMMENTARY
(Product) hide
LITERATURE
(Product)
Reversibility
r=reversible
ir=irreversible
?=not specified
5'-adenylyl sulfate + thioredoxin
AMP + sulfite + thioredoxin disulfide
show the reaction diagram
NATURAL SUBSTRATE
NATURAL PRODUCT
REACTION DIAGRAM
ORGANISM
UNIPROT
COMMENTARY
(Substrate) hide
LITERATURE
(Substrate)
COMMENTARY
(Product) hide
LITERATURE
(Product)
REVERSIBILITY
r=reversible
ir=irreversible
?=not specified
5'-adenylyl sulfate + thioredoxin
AMP + sulfite + thioredoxin disulfide
show the reaction diagram
involved in assimilatory sulfate reduction
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?
COFACTOR
ORGANISM
UNIPROT
COMMENTARY hide
LITERATURE
IMAGE
ORGANISM
COMMENTARY hide
LITERATURE
UNIPROT
SEQUENCE DB
SOURCE
UNIPROT
ENTRY NAME
ORGANISM
NO. OF AA
NO. OF TRANSM. HELICES
MOLECULAR WEIGHT[Da]
SOURCE
SEQUENCE
LOCALIZATION PREDICTION?
CYSH_BURCE
250
0
27881
Swiss-Prot
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REF.
AUTHORS
TITLE
JOURNAL
VOL.
PAGES
YEAR
ORGANISM (UNIPROT)
PUBMED ID
SOURCE
Bick, J.A.; Dennis, J.J.; Zylstra, G.J.; Nowack, J.; Leustek, T.
Identification of a new class of 5'-adenylylsulfate (APS) reductases from sulfate-assimilating bacteria
J. Bacteriol.
182
135-142
2000
Burkholderia cepacia (Q9RFS6), Burkholderia cepacia DBO1 / ATCC 29424 (Q9RFS6), Mycobacterium sp., Pseudomonas aeruginosa (O05927), Pseudomonas putida, Ralstonia pickettii, Rhizobium tropici
Manually annotated by BRENDA team