Ligand thioredoxin disulfide

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Basic Ligand Information

Molecular Structure
Picture of thioredoxin disulfide (click for magnification)
Molecular Formula
BRENDA Name
InChIKey
C30H39 2N9O6RS2
thioredoxin disulfide
XIVLQXBVJWTBPH-SVXFZJLFSA-N
Synonyms:
oxidized thioredoxin


Show all pahtways known for Show all BRENDA pathways known for thioredoxin disulfide

Roles as Enzyme Ligand

In Vivo Substrate in Enzyme-catalyzed Reactions (7 results)

EC NUMBER
PROVEN IN VIVO REACTION
REACTION DIAGRAM
LITERATURE
ENZYME 3D STRUCTURE
prostamide F2alpha + oxidized thioredoxin = prostamide H2 + reduced thioredoxin
show the reaction diagram
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2'-deoxyribonucleoside triphosphate + oxidized thioredoxin + H2O = ribonucleoside triphosphate + reduced thioredoxin
show the reaction diagram
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acetyl phosphate + ammonia + thioredoxin disulfide = glycine + phosphate + thioredoxin
show the reaction diagram
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thioredoxin disulfide + NADPH + H+ = thioredoxin + NADP+
show the reaction diagram
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reduced ferredoxin + thioredoxin disulfide = oxidized ferredoxin + thioredoxin + H+
show the reaction diagram
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In Vivo Product in Enzyme-catalyzed Reactions (55 results)

EC NUMBER
PROVEN IN VIVO REACTION
REACTION DIAGRAM
LITERATURE
ENZYME 3D STRUCTURE
2 thioredoxin + ROOH = thioredoxin disulfide + H2O + ROH
show the reaction diagram
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arsenate + thioredoxin = arsenite + thioredoxin disulfide + H2O
show the reaction diagram
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glycine + phosphate + thioredoxin = acetyl phosphate + ammonia + thioredoxin disulfide
show the reaction diagram
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N-methylglycine + phosphate + thioredoxin = acetyl phosphate + methylamine + thioredoxin disulfide
show the reaction diagram
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N,N,N-trimethylglycine + phosphate + thioredoxin = acetyl phosphate + trimethylamine + thioredoxin disulfide
show the reaction diagram
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thioredoxin + NADP+ = thioredoxin disulfide + NADPH + H+
show the reaction diagram
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5'-adenylyl sulfate + thioredoxin = AMP + sulfite + thioredoxin disulfide
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oxidized ferredoxin + thioredoxin + H+ = reduced ferredoxin + thioredoxin disulfide
show the reaction diagram
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peroxiredoxin-(S-hydroxy-S-oxocysteine) + ATP + 2 thioredoxin = peroxiredoxin-(S-hydroxycysteine) + ADP + phosphate + thioredoxin disulfide
show the reaction diagram
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Substrate in Enzyme-catalyzed Reactions (19 results)

EC NUMBER
REACTION
REACTION DIAGRAM
LITERATURE
ENZYME 3D STRUCTURE
prostamide F2alpha + oxidized thioredoxin = prostamide H2 + reduced thioredoxin
show the reaction diagram
-
2'-deoxyribonucleoside triphosphate + oxidized thioredoxin + H2O = ribonucleoside triphosphate + reduced thioredoxin
show the reaction diagram
-
acetyl phosphate + ammonia + thioredoxin disulfide = glycine + phosphate + thioredoxin
show the reaction diagram
-
L-methionine + thioredoxin disulfide + H2O = L-methionine (R)-S-oxide + thioredoxin
show the reaction diagram
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sulfinic form of peroxiredoxin IIF + oxidized thioredoxin = ? + reduced thioredoxin
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Product in Enzyme-catalyzed Reactions (145 results)

EC NUMBER
REACTION
REACTION DIAGRAM
LITERATURE
ENZYME 3D STRUCTURE
2,3-epoxyphylloquinone + reduced thioredoxin = phylloquinone + oxidized thioredoxin
show the reaction diagram
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arsenate + thioredoxin = arsenite + thioredoxin disulfide + H2O
show the reaction diagram
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glycine + phosphate + thioredoxin = acetyl phosphate + ammonia + thioredoxin disulfide
show the reaction diagram
-
-
N-methylglycine + phosphate + thioredoxin = acetyl phosphate + methylamine + thioredoxin disulfide
show the reaction diagram
-
N,N,N-trimethylglycine + phosphate + thioredoxin = acetyl phosphate + trimethylamine + thioredoxin disulfide
show the reaction diagram
-
5'-adenylyl sulfate + thioredoxin = AMP + sulfite + thioredoxin disulfide
show the reaction diagram
-
-
oxidized ferredoxin + thioredoxin + H+ = reduced ferredoxin + thioredoxin disulfide
show the reaction diagram
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adenylyl sulfate + reduced thioredoxin = AMP + sulfite + oxidized thioredoxin
show the reaction diagram
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Enzyme Kinetic Parameters

kcat Value (Turnover Number) (21 results)

EC NUMBER
TURNOVER NUMBER [1/S]
TURNOVER NUMBER MAXIMUM [1/S]
COMMENTARY
LITERATURE

KM Value (23 results)

EC NUMBER
KM VALUE [MM]
KM VALUE MAXIMUM [MM]
COMMENTARY
LITERATURE

References & Links

Links to other databases for thioredoxin disulfide

ChEBI
PubChem
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PubChem