Reference on EC 1.3.5.1 - succinate dehydrogenase and Organism(s) Homo sapiens and UniProt Accession P21912
Please use the Reference Search for a specific query.
Please wait a moment until all data is loaded. This message will disappear when all data is loaded.
topREF. 
AUTHORS
TITLE
JOURNAL
VOL.
PAGES
YEAR
ORGANISM (UNIPROT)
PUBMED ID
SOURCE
Elbehti-Green, A.; Au, H.C.; Mascarello, J.T.; Ream-Robinson, D.; Scheffler, I.E.
Characterization of the human SDHC gene encoding one of the integral membrane proteins of succinate-quinone oxidoreductase in mitochondria
Gene
213
133-140
1998
Homo sapiens
Tomitsuka, E.; Goto, Y.; Taniwaki, M.; Kita, K.
Direct evidence for expression of type II flavoprotein subunit in human complex II (succinate-ubiquinone reductase)
Biochem. Biophys. Res. Commun.
311
774-779
2003
Homo sapiens
Dekker, P.B.D.; Hogendoorn, P.C.W.; Kuipers-Dijkshoorn, N.; Prins, F.A.; van Duinen, S.G.; Taschner, P.E.M.; van der Mey, A.G.L.; Cornelisse, C.J.
SDHD mutations in head and neck paragangliomas result in destabilization of complex II in the mitochondrial respiratory chain with loss of enzymatic activity and abnormal mitochondrial morphology
J. Pathol.
201
480-486
2003
Homo sapiens
Ni, Y.; Zbuk, K.M.; Sadler, T.; Patocs, A.; Lobo, G.; Edelman, E.; Platzer, P.; Orloff, M.S.; Waite, K.A.; Eng, C.
Germline mutations and variants in the succinate dehydrogenase genes in Cowden and Cowden-like syndromes
Am. J. Hum. Genet.
83
261-268
2008
Homo sapiens
Timmers, H.J.; Pacak, K.; Bertherat, J.; Lenders, J.W.; Duet, M.; Eisenhofer, G.; Stratakis, C.A.; Niccoli-Sire, P.; Tran, B.H.; Burnichon, N.; Gimenez-Roqueplo, A.P.
Mutations associated with succinate dehydrogenase D-related malignant paragangliomas
Clin. Endocrinol. (Oxf.)
68
561-566
2008
Homo sapiens
Srirangalingam, U.; Walker, L.; Khoo, B.; Macdonald, F.; Gardner, D.; Wilkin, T.J.; Skelly, R.H.; George, E.; Spooner, D.; Monson, J.P.; Grossman, A.B.; Akker, S.A.; Pollard, P.J.; Plowman, N.; Avril, N.; Berney, D.M.; Burrin, J.M.; Reznek, R.H.; Kumar, V.K.; Maher, E.R.; Chew, S.L.
Clinical manifestations of familial paraganglioma and phaeochromocytomas in succinate dehydrogenase B gene mutation carriers
Clin. Endocrinol. (Oxf.)
69
587-596
2008
Homo sapiens
Takekoshi, K.; Isobe, K.; Suzuki, H.; Nissato, S.; Kawakami, Y.; Kawai, K.; Yamada, N.
R46Q mutation in the succinate dehydrogenase B gene (SDHB) in a Japanese family with both abdominal and thoracic paraganglioma following metastasis
Endocr. J.
55
299-303
2008
Homo sapiens
Zelinka, T.; Timmers, H.J.; Kozupa, A.; Chen, C.C.; Carrasquillo, J.A.; Reynolds, J.C.; Ling, A.; Eisenhofer, G.; Lazurova, I.; Adams, K.T.; Whatley, M.A.; Widimsky, J.; Pacak, K.
Role of positron emission tomography and bone scintigraphy in the evaluation of bone involvement in metastatic pheochromocytoma and paraganglioma: specific implications for succinate dehydrogenase enzyme subunit B gene mutations
Endocr. Relat. Cancer
15
311-323
2008
Homo sapiens
Pasini, B.; McWhinney, S.R.; Bei, T.; Matyakhina, L.; Stergiopoulos, S.; Muchow, M.; Boikos, S.A.; Ferrando, B.; Pacak, K.; Assie, G.; Baudin, E.; Chompret, A.; Ellison, J.W.; Briere, J.J.; Rustin, P.; Gimenez-Roqueplo, A.P.; Eng, C.; Carney, J.A.; Stratakis, C.A.
Clinical and molecular genetics of patients with the Carney-Stratakis syndrome and germline mutations of the genes coding for the succinate dehydrogenase subunits SDHB, SDHC, and SDHD
Eur. J. Hum. Genet.
16
79-88
2008
Homo sapiens
Papaspyrou, K.; Rossmann, H.; Fottner, C.; Weber, M.M.; Mann, W.; Lackner, K.J.; Helling, K.
Malignant paraganglioma caused by a novel germline mutation of the succinate dehydrogenase D-gene - a case report
Head Neck
30
964-969
2008
Homo sapiens
Ma, R.C.; Lam, C.W.; Chan, W.B.; So, W.Y.; Tong, S.F.; Chow, C.C.; Cockram, C.S.
A Chinese family with familial paraganglioma syndrome due to succinate dehydrogenase deficiency
Hong Kong Med. J.
13
151-154
2007
Homo sapiens
Bonache, S.; Martinez, J.; Fernandez, M.; Bassas, L.; Larriba, S.
Single nucleotide polymorphisms in succinate dehydrogenase subunits and citrate synthase genes: association results for impaired spermatogenesis
Int. J. Androl.
30
144-152
2007
Homo sapiens, Homo sapiens (P21912), Homo sapiens (Q99643)
Byun, H.O.; Kim, H.Y.; Lim, J.J.; Seo, Y.H.; Yoon, G.
Mitochondrial dysfunction by complex II inhibition delays overall cell cycle progression via reactive oxygen species production
J. Cell. Biochem.
104
1747-1759
2008
Homo sapiens
Havekes, B.; Corssmit, E.P.; Jansen, J.C.; van der Mey, A.G.; Vriends, A.H.; Romijn, J.A.
Malignant paragangliomas associated with mutations in the succinate dehydrogenase D gene
J. Clin. Endocrinol. Metab.
92
1245-1248
2007
Homo sapiens
Amar, L.; Baudin, E.; Burnichon, N.; Peyrard, S.; Silvera, S.; Bertherat, J.; Bertagna, X.; Schlumberger, M.; Jeunemaitre, X.; Gimenez-Roqueplo, A.P.; Plouin, P.F.
Succinate dehydrogenase B gene mutations predict survival in patients with malignant pheochromocytomas or paragangliomas
J. Clin. Endocrinol. Metab.
92
3822-3828
2007
Homo sapiens
Lima, J.; Feijao, T.; Ferreira da Silva, A.; Pereira-Castro, I.; Fernandez-Ballester, G.; Maximo, V.; Herrero, A.; Serrano, L.; Sobrinho-Simoes, M.; Garcia-Rostan, G.
High frequency of germline succinate dehydrogenase mutations in sporadic cervical paragangliomas in northern Spain: mitochondrial succinate dehydrogenase structure-function relationships and clinical-pathological correlations
J. Clin. Endocrinol. Metab.
92
4853-4864
2007
Homo sapiens
Timmers, H.J.; Kozupa, A.; Eisenhofer, G.; Raygada, M.; Adams, K.T.; Solis, D.; Lenders, J.W.; Pacak, K.
Clinical presentations, biochemical phenotypes, and genotype-phenotype correlations in patients with succinate dehydrogenase subunit B-associated pheochromocytomas and paragangliomas
J. Clin. Endocrinol. Metab.
92
779-786
2007
Homo sapiens
Pigny, P.; Vincent, A.; Cardot Bauters, C.; Bertrand, M.; de Montpreville, V.T.; Crepin, M.; Porchet, N.; Caron, P.
Paraganglioma after maternal transmission of a succinate dehydrogenase gene mutation
J. Clin. Endocrinol. Metab.
93
1609-1615
2008
Homo sapiens
Garrel, R.; Raynaud, P.; Raingeard, I.; Muyshondt, C.; Gardiner, Q.; Guerrier, B.; Pujol, P.; Coupier, I.
An unusual succinate dehydrogenase gene mutation C in a case of laryngeal paraganglioma
J. Laryngol. Otol.
2008
1-4
2008
Homo sapiens
Hargreaves, I.P.; Duncan, A.J.; Wu, L.; Agrawal, A.; Land, J.M.; Heales, S.J.
Inhibition of mitochondrial complex IV leads to secondary loss complex II-III activity: implications for the pathogenesis and treatment of mitochondrial encephalomyopathies
Mitochondrion
7
284-287
2007
Homo sapiens
MacKenzie, E.D.; Selak, M.A.; Tennant, D.A.; Payne, L.J.; Crosby, S.; Frederiksen, C.M.; Watson, D.G.; Gottlieb, E.
Cell-permeating alpha-ketoglutarate derivatives alleviate pseudohypoxia in succinate dehydrogenase-deficient cells
Mol. Cell. Biol.
27
3282-3289
2007
Homo sapiens
Baysal, B.E.
A recurrent stop-codon mutation in succinate dehydrogenase subunit B gene in normal peripheral blood and childhood T-cell acute leukemia
PLoS ONE
2
e436
2007
Homo sapiens
Huang, K.T.; Dobrovic, A.; Fox, S.B.
No evidence for promoter region methylation of the succinate dehydrogenase and fumarate hydratase tumour suppressor genes in breast cancer
BMC Res. Notes
2
194
2009
Homo sapiens
Prasad, P.; Kant, J.A.; Wills, M.; OLeary, M.; Lovvorn, H.; Yang, E.
Loss of heterozygosity of succinate dehydrogenase B mutation by direct sequencing in synchronous paragangliomas
Cancer genet. Cytogenet.
192
82-85
2009
Homo sapiens
Richalet, J.P.; Gimenez-Roqueplo, A.P.; Peyrard, S.; Venisse, A.; Marelle, L.; Burnichon, N.; Bouzamondo, A.; Jeunemaitre, X.; Azizi, M.; Elghozi, J.L.
A role for succinate dehydrogenase genes in low chemoresponsiveness to hypoxia?
Clin. Auton. Res.
19
335-342
2009
Homo sapiens
Saito, T.; Saito, Y.; Matsumura, K.; Tsubota, Y.; Maniwa, T.; Kaneda, H.; Minami, K.; Sakaida, N.; Uemura, Y.; Kawa, G.; Yamamoto, N.; Fujii, Y.; Isobe, K.; Kawakami, Y.; Matsuda, T.; Takekoshi, K.
Novel mutation (L157X) in the succinate dehydrogenase B gene (SDHB) in a Japanese family with abdominal paraganglioma following lung metastasis
Endocr. J.
56
451-458
2009
Homo sapiens
He, J.; Makey, D.; Fojo, T.; Adams, K.T.; Havekes, B.; Eisenhofer, G.; Sullivan, P.; Lai, E.W.; Pacak, K.
Successful chemotherapy of hepatic metastases in a case of succinate dehydrogenase subunit B-related paraganglioma
Endocrine
36
189-193
2009
Homo sapiens
Goffrini, P.; Ercolino, T.; Panizza, E.; Giache, V.; Cavone, L.; Chiarugi, A.; Dima, V.; Ferrero, I.; Mannelli, M.
Functional study in a yeast model of a novel succinate dehydrogenase subunit B gene germline missense mutation (C191Y) diagnosed in a patient affected by a glomus tumor
Hum. Mol. Genet.
18
1860-1868
2009
Saccharomyces cerevisiae, Homo sapiens
Cervera, A.M.; Bayley, J.P.; Devilee, P.; McCreath, K.J.
Inhibition of succinate dehydrogenase dysregulates histone modifications in mammalian cells
Mol. Cancer
8
89
2009
Homo sapiens
Cimen, H.; Han, M.J.; Yang, Y.; Tong, Q.; Koc, H.; Koc, E.C.
Regulation of succinate dehydrogenase activity by SIRT3 in mammalian mitochondria
Biochemistry
49
304-311
2010
Homo sapiens, Mus musculus
Rutter, J.; Winge, D.R.; Schiffman, J.D.
Succinate dehydrogenase - Assembly, regulation and role in human disease
Mitochondrion
10
393-401
2010
Homo sapiens
Lemarie, A.; Huc, L.; Pazarentzos, E.; Mahul-Mellier, A.L.; Grimm, S.
Specific disintegration of complex II succinate:ubiquinone oxidoreductase links pH changes to oxidative stress for apoptosis induction
Cell Death Differ.
18
338-349
2011
Homo sapiens
Xiao, W.; Sarsour, E.H.; Wagner, B.A.; Doskey, C.M.; Buettner, G.R.; Domann, F.E.; Goswami, P.C.
Succinate dehydrogenase activity regulates PCB3-quinone-induced metabolic oxidative stress and toxicity in HaCaT human keratinocytes
Arch. Toxicol.
90
319-332
2016
Homo sapiens
Moosavi, B.; Zhu, X.; Yang, W.; Yang, G.
Genetic, epigenetic and biochemical regulation of succinate dehydrogenase function
Biol. Chem.
401
319-330
2020
Brassica sp., Caenorhabditis elegans, Thermus thermophilus, Staphylococcus aureus, Mycobacterium tuberculosis, Mus musculus, Neisseria meningitidis, Rattus norvegicus, Escherichia coli (P0AC41 AND P07014), Homo sapiens (P31040 AND P21912 AND Q99643 AND O14521), Saccharomyces cerevisiae (Q00711 AND P21801 AND P33421 AND P37298)
Moosavi, B.; Berry, E.; Zhu, X.; Yang, W.; Yang, G.
The assembly of succinate dehydrogenase a key enzyme in bioenergetics
Cell. Mol. Life Sci.
76
4023-4042
2019
Homo sapiens (P31040 AND P21912 AND Q99643 AND O14521), Homo sapiens, Saccharomyces cerevisiae (Q00711 AND P21801 AND P33421 AND P37298)
