Protein Variants | Comment | Organism |
---|---|---|
D92Y | the naturally occurring mutation of gene SDHD encoding subunit Sdh4p is involved in development of malignant paragangliomas with paraganglioma bone metastases, intrathoracic paraganglioma with lymph node metastases, locally invasive head-and-neck paraganglioma with destruction of the petrosal bone, and locally invasive paraganglioma of the bladder with lymph node metastases, phenotypes, overview | Homo sapiens |
Natural Substrates | Organism | Comment (Nat. Sub.) | Natural Products | Comment (Nat. Pro.) | Rev. | Reac. |
---|---|---|---|---|---|---|
additional information | Homo sapiens | subunit mutations are involved in development of malignant paragangliomas | ? | - |
? | |
succinate + ubiquinone | Homo sapiens | - |
fumarate + ubiquinol | - |
? |
Organism | UniProt | Comment | Textmining |
---|---|---|---|
Homo sapiens | - |
- |
- |
Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
---|---|---|---|---|---|---|
additional information | subunit mutations are involved in development of malignant paragangliomas | Homo sapiens | ? | - |
? | |
succinate + ubiquinone | - |
Homo sapiens | fumarate + ubiquinol | - |
? |
Synonyms | Comment | Organism |
---|---|---|
SDH | - |
Homo sapiens |
Cofactor | Comment | Organism | Structure |
---|---|---|---|
ubiquinone | - |
Homo sapiens |