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Information on EC 1.1.1.398 - 2-glutathionyl-2-methylbut-3-en-1-ol dehydrogenase

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IUBMB Comments
The enzyme, characterized from the bacterium Rhodococcus sp. AD45, is involved in isoprene degradation.
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The expected taxonomic range for this enzyme is: Rhodococcus sp. AD45
Synonyms
4-hydroxy-3-glutathionyl-3-methylbut-1-ene dehydrogenase, isoH, more
REACTION
REACTION DIAGRAM
COMMENTARY hide
ORGANISM
UNIPROT
LITERATURE
2-(glutathion-S-yl)-2-methylbut-3-en-1-ol + 2 NAD+ + H2O = 2-(glutathion-S-yl)-2-methylbut-3-enoate + 2 NADH + 2 H+
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overall reaction
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2-(glutathion-S-yl)-2-methylbut-3-en-1-ol + NAD+ = 2-(glutathion-S-yl)-2-methylbut-3-enal + NADH + H+
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(1a)
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2-(glutathion-S-yl)-2-methylbut-3-enal + NAD+ + H2O = 2-(glutathion-S-yl)-2-methylbut-3-enoate + NADH + H+
show the reaction diagram
(1b)
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