Reference on EC 1.1.1.267 - 1-deoxy-D-xylulose-5-phosphate reductoisomerase and Organism(s) Plasmodium falciparum and UniProt Accession Q8IKG4
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AUTHORS
TITLE
JOURNAL
VOL.
PAGES
YEAR
ORGANISM (UNIPROT)
PUBMED ID
SOURCE
Wiesner, J.; Hintz, M.; Altincicek, B.; Sanderbrand, S.; Weidemeyer, C.; Beck, E.; Jomaa, H.
Plasmodium falciparum: Detection of the deoxyxylulose 5-phosphate reductoisomerase activity
Exp. Parasitol.
96
182-186
2000
Plasmodium falciparum
Singh, N.; Cheve, G.; Avery, M.A.; McCurdy, C.R.
Comparative protein modeling of 1-deoxy-D-xylulose-5-phosphate reductoisomerase enzyme from Plasmodium falciparum: a potential target for antimalarial drug discovery
J. Chem. Inf. Model.
46
1360-1370
2006
Plasmodium falciparum (O96693), Plasmodium falciparum
Tahar, R.; Basco, L.K.
Molecular epidemiology of malaria in Cameroon. XXV. In vitro activity of fosmidomycin and its derivatives against fresh clinical isolates of Plasmodium falciparum and sequence analysis of 1-deoxy-D-xylulose 5-phosphate reductoisomerase
Am. J. Trop. Med. Hyg.
77
214-220
2007
Plasmodium falciparum (O96693), Plasmodium falciparum
Giessmann, D.; Heidler, P.; Haemers, T.; Van Calenbergh, S.; Reichenberg, A.; Jomaa, H.; Weidemeyer, C.; Sanderbrand, S.; Wiesner, J.; Link, A.
Towards new antimalarial drugs: synthesis of non-hydrolyzable phosphate mimics as feed for a predictive QSAR study on 1-deoxy-D-xylulose-5-phosphate reductoisomerase inhibitors
Chem. Biodivers.
5
643-656
2008
Escherichia coli, Plasmodium falciparum
Umeda, T.; Tanaka, N.; Kusakabe, Y.; Nakanishi, M.; Kitade, Y.; Nakamura, K.T.
Crystallization and preliminary X-ray crystallographic study of 1-deoxy-D-xylulose 5-phosphate reductoisomerase from Plasmodium falciparum
Acta Crystallogr. Sect. F
66
330-332
2010
Plasmodium falciparum
Goble, J.L.; Adendorff, M.R.; de Beer, T.A.; Stephens, L.L.; Blatch, G.L.
The malarial drug target Plasmodium falciparum 1-deoxy-D-xylulose-5-phosphate reductoisomerase (PfDXR): development of a 3-D model for identification of novel, structural and functional features and for inhibitor screening
Protein Pept. Lett.
17
109-120
2010
Plasmodium falciparum (Q8IKG4), Plasmodium falciparum
Xue, J.; Diao, J.; Cai, G.; Deng, L.; Zheng, B.; Yao, Y.; Song, Y.
Antimalarial and structural studies of pyridine-containing inhibitors of 1-deoxyxylulose-5-phosphate reductoisomerase
ACS Med. Chem. Lett.
4
278-282
2013
Escherichia coli, Plasmodium falciparum (O96693), Plasmodium falciparum
Bodill, T.; Conibear, A.C.; Mutorwa, M.K.; Goble, J.L.; Blatch, G.L.; Lobb, K.A.; Klein, R.; Kaye, P.T.
Exploring DOXP-reductoisomerase binding limits using phosphonated N-aryl and N-heteroarylcarboxamides as DXR inhibitors
Bioorg. Med. Chem.
21
4332-4341
2013
Escherichia coli, Plasmodium falciparum
Kesharwani, S.; Sundriyal, S.
Non-hydroxamate inhibitors of 1-deoxy-D-xylulose 5-phosphate reductoisomerase (DXR) a critical review and future perspective
Eur. J. Med. Chem.
213
113055
2021
Escherichia coli (P45568), Mycobacterium tuberculosis (P9WNS1), Plasmodium falciparum (Q8IKG4), Mycobacterium tuberculosis H37Rv (P9WNS1), Mycobacterium tuberculosis ATCC 25618 (P9WNS1)
Sharma, D.; Dada, R.; Tejavath, K.; Rai, P.; Soni, R.; Yaragorla, S.; Bhatt, T.
A paradigm towards the antimalarial quest in silico identification and biological evaluation of novel inhibitors targeting 1-deoxy-D-xylulose-5-phosphate reductoisomerase
J. Biomol. Struct. Dyn.
38
295-301
2020
Plasmodium falciparum (Q8IKG4)
Wadood, A.; Ghufran, M.; Hassan, S.; Khan, H.; Azam, S.; Rashid, U.
In silico identification of promiscuous scaffolds as potential inhibitors of 1-deoxy-D-xylulose 5-phosphate reductoisomerase for treatment of falciparum malaria
Pharm. Biol.
55
19-32
2017
Plasmodium falciparum (Q8IKG4), Plasmodium falciparum
