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Information on EC 1.1.1.110 - aromatic 2-oxoacid reductase

for references in articles please use BRENDA:EC1.1.1.110
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IUBMB Comments
The enzymes from anaerobic bacteria such as Clostridium sporogenes participate in the fermentation pathways of L-phenylalanine, L-tyrosine and L-tryptophan. The enzyme from the yeast Candida maltosa has similar activity, but, unlike the bacterial enzyme, requires Mn2+ and can also use NADPH with lower activity.
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Word Map
The expected taxonomic range for this enzyme is: Eukaryota, Bacteria
Synonyms
(indol-3-yl)lactate:NAD+ oxidoreductase, (R)-aromatic lactate dehydrogenase, D-aryllactate D-hydrogenase, indolelactate dehydrogenase, more
REACTION
REACTION DIAGRAM
COMMENTARY hide
ORGANISM
UNIPROT
LITERATURE
(R)-(indol-3-yl)lactate + NAD+ = (indol-3-yl)pyruvate + NADH + H+
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(3)
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(R)-3-(4-hydroxyphenyl)lactate + NAD+ = 3-(4-hydroxyphenyl)pyruvate + NADH + H+
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; (2)
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