2.5.1.127: caldopentamine synthase
This is an abbreviated version!
For detailed information about caldopentamine synthase, go to the full flat file.
Reaction
Synonyms
HbSpe II, long-chain polyamine synthase
ECTree
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Systematic Name
Systematic Name on EC 2.5.1.127 - caldopentamine synthase
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S-adenosyl 3-(methylthio)propylamine:norspermine 3-aminopropyltransferase
The enzyme, characterized from the thermophilic archaeon Hyperthermus butylicus, can also synthesize norspermine from norspermidine and thermospermine from spermidine (with lower activity). The long-chain polyamines stabilize double-stranded DNA at high temperatures. In contrast to EC 2.5.1.23, sym-norspermidine synthase and EC 2.5.1.126, norspermine synthase, this enzyme shows no activity with propane-1,3-diamine.