2.4.1.364: protopanaxadiol-type ginsenoside 3-O-glucosyltransferase

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For detailed information about protopanaxadiol-type ginsenoside 3-O-glucosyltransferase, go to the full flat file.

Reaction

Synonyms

3GT1, Pq3-O-UGT1, UGT74AE2

ECTree

2 Transferases

2.4 Glycosyltransferases

2.4.1 Hexosyltransferases

2.4.1.364 protopanaxadiol-type ginsenoside 3-O-glucosyltransferase

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Results	in table
2	AA Sequence
2	Cloned(Commentary)
1	Expression
2	General Information
2	kcat/KM [mM/s]
2	KM Value [mM]
4	Natural Substrates/ Products (Substrates)
3	Organism
3	Pathway
1	Purification (Commentary)
2	Reaction
3	Reference
4	Source Tissue
6	Substrates and Products (Substrate)
1	Subunits
5	Synonyms
1	Systematic Name
2	Turnover Number [1/s]

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General Information on EC 2.4.1.364 - protopanaxadiol-type ginsenoside 3-O-glucosyltransferase

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metabolism

Panax ginseng

A0A0A6ZFR4

key enzyme for the synthesis of ginsenosides

751849

physiological function

Panax quinquefolius

A0A0M4LS39

overexpression of Pq3-O-UGT1 leads to a higher level of protopanaxadiol-group ginsenosides (especially for Rh2 and Rd) in transgenic hairy roots, whereas RNA interference against Pq3-O-UGT1 results in lower content of ginsenoside Rh2. Both overexpression and RNAi upregulate the key upstream genes Pq-D12H and Pq-CYP6H, and there is no effect on the upstream gene of Pq-DS

759949