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Literature summary for 2.4.1.364 extracted from

  • Lu, C.; Zhao, S.; Wang, X.
    Functional regulation of a UDP-glucosyltransferase gene (Pq3-O-UGT1) by RNA interference and overexpression in Panax quinquefolius (2017), Plant Cell Tissue Organ Cult., 129, 445-456 .
No PubMed abstract available

Cloned(Commentary)

Cloned (Comment) Organism
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Panax quinquefolius

Organism

Organism UniProt Comment Textmining
Panax quinquefolius A0A0M4LS39
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-

Source Tissue

Source Tissue Comment Organism Textmining
root hairy root Panax quinquefolius
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Substrates and Products (Substrate)

Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
UDP-alpha-D-glucose + (20S)-protopanaxadiol
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Panax quinquefolius UDP + (20S)-ginsenoside Rh2
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?

Subunits

Subunits Comment Organism
? x * 51100, calculated from sequence Panax quinquefolius

Synonyms

Synonyms Comment Organism
3GT1
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Panax quinquefolius
Pq3-O-UGT1
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Panax quinquefolius

Expression

Organism Comment Expression
Panax quinquefolius expression in hairy root is increased by methyl jasmonate up

General Information

General Information Comment Organism
physiological function overexpression of Pq3-O-UGT1 leads to a higher level of protopanaxadiol-group ginsenosides (especially for Rh2 and Rd) in transgenic hairy roots, whereas RNA interference against Pq3-O-UGT1 results in lower content of ginsenoside Rh2. Both overexpression and RNAi upregulate the key upstream genes Pq-D12H and Pq-CYP6H, and there is no effect on the upstream gene of Pq-DS Panax quinquefolius