2.1.1.B109: tRNA (cytosine32-N3)-methyltransferase

This is an abbreviated version!
For detailed information about tRNA (cytosine32-N3)-methyltransferase, go to the full flat file.

Reaction

Synonyms

Abp140p, methyltransferase-like protein 2B, METTL2B, Trm140p

ECTree

     2 Transferases

         2.1 Transferring one-carbon groups

             2.1.1 Methyltransferases

                2.1.1.B109 tRNA (cytosine32-N3)-methyltransferase

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Results	in table
1	AA Sequence
1	Cloned(Commentary)
2	Cofactor
8	General Information
2	Localization
2	Molecular Weight [Da]
3	Natural Substrates/ Products (Substrates)
28	Organism
1	pH Optimum
12	Protein Variants
1	Purification (Commentary)
5	Reaction
3	Reference
7	Substrates and Products (Substrate)
5	Subunits
8	Synonyms
1	Systematic Name
1	Temperature Optimum [°C]

Substrates Products

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Substrates Products on EC 2.1.1.B109 - tRNA (cytosine32-N3)-methyltransferase

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SUBSTRATE

PRODUCT                       

REACTION DIAGRAM

ORGANISM

UNIPROT

COMMENTARY
(Substrate)

LITERATURE
(Substrate)

COMMENTARY
(Product)

LITERATURE
(Product)

Reversibility
r=reversible
ir=irreversible
?=not specified

S-adenosyl-L-methionine + cytosine32 in tRNASer/Thr

S-adenosyl-L-homocysteine + N3-methylcytosine32 in tRNASer/Thr

5 entries

additional information

?

-

2 entries

S-adenosyl-L-methionine + cytosine32 in tRNASer/Thr

S-adenosyl-L-homocysteine + N3-methylcytosine32 in tRNASer/Thr

Homo sapiens

Q6P1Q9

-

721028

-

-

?

S-adenosyl-L-methionine + cytosine32 in tRNASer/Thr

S-adenosyl-L-homocysteine + N3-methylcytosine32 in tRNASer/Thr

Saccharomyces cerevisiae

-

-

721028

-

-

?

S-adenosyl-L-methionine + cytosine32 in tRNASer/Thr

S-adenosyl-L-homocysteine + N3-methylcytosine32 in tRNASer/Thr

Saccharomyces cerevisiae

-

tRNASer1 is not methylated by Abp140p under the same condition as the methylation of tRNAThr1 in vitro, overview. Some essential factor(s) is required for m3C formation in tRNASer1

721028

mass spectrometric analysis of tRNA products

-

?

S-adenosyl-L-methionine + cytosine32 in tRNASer/Thr

S-adenosyl-L-homocysteine + N3-methylcytosine32 in tRNASer/Thr

Saccharomyces cerevisiae BY4742

-

-

721028

-

-

?

S-adenosyl-L-methionine + cytosine32 in tRNASer/Thr

S-adenosyl-L-homocysteine + N3-methylcytosine32 in tRNASer/Thr

Saccharomyces cerevisiae BY4742

-

tRNASer1 is not methylated by Abp140p under the same condition as the methylation of tRNAThr1 in vitro, overview. Some essential factor(s) is required for m3C formation in tRNASer1

721028

mass spectrometric analysis of tRNA products

-

?

additional information

?

-

Saccharomyces cerevisiae

-

secondary structures of Saccharomyces cerevisiae tRNAThr1 and tRNASer1 with modified nucleosides, including 3-methylcytidine, overview

721028

-

-

?

additional information

?

-

Saccharomyces cerevisiae BY4742

-

secondary structures of Saccharomyces cerevisiae tRNAThr1 and tRNASer1 with modified nucleosides, including 3-methylcytidine, overview

721028

-

-

?