Any feedback?
Please rate this page
(all_enzymes.php)
(0/150)

BRENDA support

1.14.14.175: ferruginol synthase

This is an abbreviated version!
For detailed information about ferruginol synthase, go to the full flat file.

Word Map on EC 1.14.14.175

Reaction

abieta-8,11,13-triene
+
[reduced NADPH-hemoprotein reductase]
 +
O2
=
ferruginol
 +
[oxidized NADPH-hemoprotein reductase]
 +
H2O

Synonyms

CYP76AH1, Cyp76AH22, Cyp76AH23, CYP76AH24, CYP76AH4, EC 1.14.13.190, FS1, FS2, miltiradiene oxidase, miltiradiene,NADPH:oxygen oxidoreductase (ferruginol forming)

ECTree

     1 Oxidoreductases
         1.14 Acting on paired donors, with incorporation or reduction of molecular oxygen
             1.14.14 With reduced flavin or flavoprotein as one donor, and incorporation of one atom of oxygen into the other donor
                1.14.14.175 ferruginol synthase

Natural Substrates Products

Natural Substrates Products on EC 1.14.14.175 - ferruginol synthase

Please wait a moment until all data is loaded. This message will disappear when all data is loaded.
NATURAL SUBSTRATE
NATURAL PRODUCT
REACTION DIAGRAM
ORGANISM
UNIPROT
COMMENTARY
(Substrate) hide
LITERATURE
(Substrate)
COMMENTARY
(Product) hide
LITERATURE
(Product)
REVERSIBILITY
r=reversible
ir=irreversible
?=not specified
abieta-8,11,13-triene + O2
ferruginol + H2O
show the reaction diagram
-
abieta-8,11,13-triene is formed spontaneously from miltiradiene. This reaction may be catalyzed by a not yet identified enzyme
-
-
?
abieta-8,11,13-triene + [reduced NADPH-hemoprotein reductase] + O2
abieta-8,11,13-trien-12-ol + [oxidized NADPH-hemoprotein reductase] + H2O
show the reaction diagram
-
-
-
?
abieta-8,11,13-triene + [reduced NADPH-hemoprotein reductase] + O2
ferruginol + [oxidized NADPH-hemoprotein reductase] + H2O
show the reaction diagram
-
-
-
?
additional information
?
-
CYP76AH1, catalyzes a four-electron oxidation cascade on miltiradiene to produce ferruginol both in vitro and in vivo
-
-
-