EC Number   |
Protein Variants |
Reference |
|---|
   3.1.3.9 | D38V |
the mutation leads to reduced levels of G6PC protein |
698186 |
| 3.1.3.9 | E110Q |
the mutation retains 16% of wild type activity |
698186 |
| 3.1.3.9 | F322L |
mutant has similar stability to wild type enzyme |
698186 |
| 3.1.3.9 | F327del/V338F/I341N/L345R |
the mutation leads to reduced levels of G6PC protein |
698186 |
| 3.1.3.9 | G122D |
mutant has similar stability to wild type enzyme |
698186 |
| 3.1.3.9 | G188D/G188S/G188R |
the mutation leads to reduced levels of G6PC protein |
698186 |
| 3.1.3.9 | G222R |
the mutation retains 2.6% of wild type activity |
698186 |
| 3.1.3.9 | G350X |
the mutation retains 41.5% of wild type activity |
698186 |
| 3.1.3.9 | H119A |
mutation inactivates the phosphatase |
652292 |
| 3.1.3.9 | H119L |
the mutation completely abolishes enzymatic activity |
698186 |
