EC Number   |
pH Minimum |
pH Maximum |
Reference |
|---|
    4.6.1.1 | -999 |
- |
ciliary beat frequency is stimulated by cAMP independently of intracellular pH |
681169 |
| 4.6.1.1 | -999 |
- |
crystal forms of the native and His tagged enzyme appear to require pH below 5 |
677339 |
| 4.6.1.1 | 4.8 |
8 |
holoenzyme |
666924 |
| 4.6.1.1 | 5 |
8 |
- |
681435 |
| 4.6.1.1 | 5.3 |
8 |
approx. 20% of maximal activity at pH 5.3, approx. 50% of maximal activity at pH 8.0, recombinant CyaB1-maltose binding protein fusion |
653017 |
| 4.6.1.1 | 5.5 |
8 |
isolated catalytic domain Rv1264 211-397, uniformly high enzyme activity |
666924 |
| 4.6.1.1 | 5.5 |
8 |
the Rv1264 holoenzyme shows higher adenylyl cyclase activity at pH 6.0. In contrast, the purified cyclase domain shows similar activities at both pH 5.5 and pH 8.0, pH sensing is not a property of any single amino acid in Rv1264 but a property of a network of interactions between the N-terminal and cyclase domains |
679824 |
| 4.6.1.1 | 6 |
8 |
upon a shift from pH 8 to 6, Rv1264 is activated 40fold, pH sensitivity is linked to the N-terminal domain |
679129 |
| 4.6.1.1 | 6.5 |
9 |
holoenzyme has a 5fold higher activity at pH 6.5 compared to activity at pH 9, and with the catalytic domain the maximal activity difference in activity is 3fold between pH 6.5 and 7.6 |
679750 |
| 4.6.1.1 | 6.5 |
9.5 |
- |
678029 |
